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肢体-体壁复合畸形的罕见病例报告

A Rare Case Report of Limb Body Wall Complex.

作者信息

Narayan Ruchika, Meena Anamika, Sarkar Rajib, Agrawal Muskaan

机构信息

Radiodiagnosis, All India Institute of Medical Sciences, Patna, IND.

出版信息

Cureus. 2024 Apr 25;16(4):e59026. doi: 10.7759/cureus.59026. eCollection 2024 Apr.

Abstract

Limb body wall complex (LBWC), also known as body stalk anomaly, is a rare and lethal disorder of the anterior abdominal wall. It is characterized by a severe combination of congenital malformations in the fetus, including, abdomino- and/or thoracoschisis, exencephaly/encephalocele, limb deformities, and facial clefts. Short umbilical cord, abdominal placental attachment, and spinal anomalies are among other manifestations of this disorder. The cause of LBWC is still unknown. The main hypotheses include embryonic dysplasia, early amniotic rupture, and vascular accident during embryonic development. We present a case of LBWC that was detected prenatally on ultrasound (USG) imaging and later confirmed postnatally in a Rh-negative mother at the menstrual age of 14 weeks.

摘要

肢体-体壁综合征(LBWC),也称为体蒂异常,是一种罕见的致命性前腹壁疾病。其特征是胎儿出现严重的先天性畸形组合,包括腹裂和/或胸裂、无脑儿/脑膨出、肢体畸形和面部裂隙。短脐带、胎盘附着于腹部以及脊柱异常是该疾病的其他表现。LBWC的病因尚不清楚。主要假说是胚胎发育异常、早期羊膜破裂以及胚胎发育期间的血管意外。我们报告一例在孕14周经超声(USG)成像产前检测到、后在一名Rh阴性母亲产后确诊的LBWC病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ebf/11127772/d78ba3bbb6dd/cureus-0016-00000059026-i01.jpg

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