Internal Medicine, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA
Internal Medicine, Michigan State University College of Human Medicine, East Lansing, Michigan, USA.
BMJ Case Rep. 2024 May 27;17(5):e258709. doi: 10.1136/bcr-2023-258709.
A man in his 20s with a medical history of syphilis, chlamydia and HIV presented to the emergency department (ED) with 2 months of right hip pain and was found to have advanced avascular necrosis (AVN) of the right femoral head with secondary haemorrhage. The patient lacked the common risk factors of AVN in patients with HIV (PWH): ≥10 years of HIV diagnosis, extended duration on highly active antiretroviral therapy, trauma, corticosteroid use, alcohol abuse, systemic lupus erythematosus, obesity, smoking and dyslipidaemia. Given the extensive destructive changes in the hip joint and muscles, a right hip resection arthroplasty was performed, and the patient recovered well postoperatively. This case presents a learning opportunity for understanding bone pathologies in PWH and offers clinical guidance for the management of HIV-infected patients with a focus on optimising bone health.
一位 20 多岁的男性,有梅毒、衣原体和 HIV 的病史,因右髋部疼痛 2 个月就诊于急诊科,被发现患有右侧股骨头严重的缺血性坏死(AVN)并伴有继发性出血。该患者缺乏 HIV 感染者发生 AVN 的常见危险因素:HIV 诊断时间≥10 年,长期接受高效抗逆转录病毒治疗,创伤,皮质类固醇使用,酗酒,系统性红斑狼疮,肥胖,吸烟和血脂异常。鉴于髋关节和肌肉广泛的破坏性变化,进行了右髋关节切除关节成形术,患者术后恢复良好。该病例为了解 HIV 感染者的骨骼病理学提供了学习机会,并为管理重点是优化骨骼健康的 HIV 感染患者提供了临床指导。