Blekinge Hospital, Karlskrona, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Acta Paediatr. 2024 Aug;113(8):1796-1802. doi: 10.1111/apa.17302. Epub 2024 May 27.
This study aimed to investigate the risks of intraventricular haemorrhage (IVH) or sepsis in extremely and very preterm infants exposed to early skin-to-skin contact (SSC).
Data from the Swedish Neonatal Quality Register from 2015 to 2021 were extracted to compare the proportions of infants exposed and not exposed to SSC on day 0 and/or 1 in life that developed IVH or sepsis.
A total of 2514 infants, 1005 extremely preterm and 1509 very preterm, were included. This amounted to 69% of all extremely and very preterm infants born during the study period. The proportion of infants with IVH exposed and not exposed to early SSC was 11% and 27%, an adjusted odds ratio (aOR) of 0.67 (95%CI 0.52-0.86, p = 0.002). The proportion of infants with sepsis exposed and not exposed to early SSC was 16% and 30%, an aOR of 0.94 (95%CI 0.75-1.2, p = 0.60). For extremely preterm infants, the proportion with sepsis when exposed and not exposed to early SSC was 29% and 44%, an aOR of 0.65 (95%CI 0.46-0.92, p = 0.015).
In the current setting, the risk of IVH or sepsis is not increased when an extremely or very preterm infant is exposed to early SSC.
本研究旨在探讨早期皮肤接触（SSC）对极低和极早产儿发生脑室出血（IVH）或败血症风险的影响。
从 2015 年至 2021 年，我们从瑞典新生儿质量登记处提取数据，比较在生命第 0 天和/或第 1 天接受和未接受 SSC 的婴儿中 IVH 或败血症的发生比例。
共纳入 2514 名婴儿，1005 名极早产儿和 1509 名非常早产儿，占研究期间所有极早产儿和非常早产儿的 69%。接受和未接受早期 SSC 的婴儿中 IVH 的比例分别为 11%和 27%，调整后的优势比（aOR）为 0.67（95%CI 0.52-0.86，p=0.002）。接受和未接受早期 SSC 的婴儿中败血症的比例分别为 16%和 30%，aOR 为 0.94（95%CI 0.75-1.2，p=0.60）。对于极早产儿，接受和未接受早期 SSC 的婴儿中败血症的比例分别为 29%和 44%，aOR 为 0.65（95%CI 0.46-0.92，p=0.015）。
在当前环境下，暴露于早期 SSC 的极低或极早产儿发生 IVH 或败血症的风险并未增加。
Zotero 插件