Akai Koki, Nagai Koutatsu, Tsuji Shotaro, Hirose Katsuyoshi, Maruyama Daisuke, Matsuzawa Ryota, Tamaki Kayoko, Kusunoki Hiroshi, Wada Yosuke, Shinmura Ken
Department of Rehabilitation, JCHO Osaka Hospital, Osaka 553-0003, Japan.
Department of Physical therapy, School of Rehabilitation, Hyogo Medical University, Kobe 650-8530, Japan.
Geriatrics (Basel). 2024 May 11;9(3):62. doi: 10.3390/geriatrics9030062.
Bone quality is an essential factor determining bone strength. However, the relationship between physical activity (PA) and bone quality remains unclear. This study aimed to ascertain the relationship between bone quality and PA using a cortical bone quantitative ultrasound device that measures components of bone quality. In this cross-sectional study, bone quality was assessed in community-dwelling older adults by measuring the cortical speed of sound (cSOS) at the mid-tibia using a quantitative ultrasound device. Using a wrist-worn accelerometer, we calculated the daily duration of moderate-to-vigorous physical activity (MVPA) and light physical activity (LPA) based on estimated METs from the accelerometer data, without differentiating between types of activities. A multiple regression analysis was performed to examine the association between PA and the cSOS. The participants' physical activity averaged 42.0 min/day for MVPA and 483.6 min/day for LPA. No significant association was observed between PA and bone quality in either men or women in the crude models. Furthermore, PA was not significantly correlated with the cSOS in the models adjusted for age, body mass index, nutrient intake, number of medications, and kidney disease. This study was a cross-sectional study which focused on the association between bone quality in older adults and their current amount of PA. The cSOS, as a measure of bone quality, was not associated with PA in men or women. Higher amounts of daily PA, as estimated from metabolic equivalents with an accelerometer, may not necessarily maintain or improve bone quality in older adults. This study does not rule out the potential for a positive association between PA levels or types and bone quality in younger or middle-aged individuals. It was specifically targeted at older adults, and its findings should not be generalized to younger populations. Further longitudinal studies are required to better understand the relationship between PA and bone quality.
骨质量是决定骨强度的一个重要因素。然而，身体活动（PA）与骨质量之间的关系仍不清楚。本研究旨在使用一种测量骨质量成分的皮质骨定量超声设备，确定骨质量与PA之间的关系。在这项横断面研究中，通过使用定量超声设备测量胫骨中部的皮质骨声速（cSOS），对社区居住的老年人的骨质量进行评估。我们使用腕部佩戴的加速度计，根据加速度计数据估算的代谢当量，计算中度至剧烈身体活动（MVPA）和轻度身体活动（LPA）的每日时长，而不区分活动类型。进行多元回归分析以检验PA与cSOS之间的关联。参与者的身体活动平均MVPA为每天42.0分钟，LPA为每天483.6分钟。在粗模型中，男性和女性的PA与骨质量之间均未观察到显著关联。此外，在对年龄、体重指数、营养摄入、药物数量和肾脏疾病进行校正的模型中，PA与cSOS也无显著相关性。本研究是一项横断面研究，重点关注老年人的骨质量与其当前PA量之间的关联。作为骨质量指标的cSOS与男性或女性的PA均无关联。通过加速度计以代谢当量估算的较高每日PA量，不一定能维持或改善老年人的骨质量。本研究并不排除PA水平或类型与年轻或中年个体骨质量之间存在正相关的可能性。它专门针对老年人，其研究结果不应推广到年轻人群体。需要进一步的纵向研究，以更好地理解PA与骨质量之间的关系。
