Todorovic Markovic Marija, Todorovic Mitic Mirjana, Ignjatovic Aleksandra, Gottfredsson Magnús, Gaini Shahin
Department of Cardiology, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Department of Infectious Diseases, Odense University Hospital, 5000 Odense, Denmark.
Infect Dis Rep. 2024 May 13;16(3):448-457. doi: 10.3390/idr16030033.
The aim of this study was to collect data and analyze mortality among patients hospitalized with community-acquired infections in the Faroe Islands. A prospective observational study was conducted in the Medical Department of the National Hospital of the Faroe Islands from October 2013 to April 2015. Cumulative all-cause, in-hospital, short-term, intermediate-term and long-term mortality rates were calculated. Kaplan-Meier survival curves comparing infection-free patients with infected patients of all severities and different age groups are presented. A log-rank test was used to compare groups. Mortality hazard ratios were calculated for subgroups using Cox regression multivariable models. There were 1309 patients without infection and 755 patients with infection. There were 51% female and 49% male patients. Mean age was 62.73 ± 19.71. Cumulative all-cause mortality and in-hospital mortality were highest in more severe forms of infection. This pattern remained the same for short-term mortality in the model adjusted for sex and age, while there were no significant differences among the various infection groups in regard to intermediate- or long-term survival after adjustment. Overall and short-term mortality rates were highest among those with severe manifestations of infection and those with infection compared to infection-free patients.
本研究的目的是收集法罗群岛社区获得性感染住院患者的数据并分析其死亡率。2013年10月至2015年4月在法罗群岛国家医院内科进行了一项前瞻性观察研究。计算了累积全因、住院、短期、中期和长期死亡率。给出了比较无感染患者与所有严重程度和不同年龄组感染患者的Kaplan-Meier生存曲线。采用对数秩检验比较各组。使用Cox回归多变量模型计算亚组的死亡风险比。共有1309例无感染患者和755例感染患者。女性患者占51%,男性患者占49%。平均年龄为62.73±19.71。在更严重的感染形式中,累积全因死亡率和住院死亡率最高。在根据性别和年龄调整的模型中,短期死亡率的情况保持不变,而调整后各感染组在中期或长期生存方面没有显著差异。与无感染患者相比,感染严重表现患者和感染患者的总体死亡率和短期死亡率最高。