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区域神经阻滞相关神经损伤:病因、风险因素和预防的文献综述。

Nerve Injury Following Regional Nerve Block: A Literature Review of Its Etiologies, Risk Factors, and Prevention.

机构信息

Department of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

University of Texas at Southwestern Medical Center, Dallas, TX, USA.

出版信息

Curr Pain Headache Rep. 2024 Sep;28(9):863-868. doi: 10.1007/s11916-024-01268-w. Epub 2024 May 28.

Abstract

PURPOSE OF REVIEW

Postoperative nerve injury after nerve block is complex and multifactorial. The mechanisms, etiologies, and risk factors are explored. This review article conducts a literature search and summarizes current evidence and best practices in prevention of nerve injury.

RECENT FINDINGS

Emerging technology such as ultrasound, injection pressure monitors, and nerve stimulators for peripheral nerve block have been incorporated into regular practice to reduce the rate of nerve injury. Studies show avoidance of intrafascicular injection, limiting concentrations/volumes of local anesthetic, and appropriate patient selection are the most significant controllable factors in limiting the negative consequences of nerve block. Peripheral nerve injury is an uncommon occurrence after nerve block and is obscured by surgical manipulation, positioning, and underlying neural integrity. Underlying neural integrity is not always evident despite an adequate history and physical exam. Surgical stress, independently of nerve block, may exacerbate these neurologic disease processes and make diagnosing a postoperative nerve injury more challenging. Prevention of nerve injury by surgical teams, care with positioning, and avoidance of intrafascicular injection with nerve block are the most evidence-based practices.

摘要

目的综述

神经阻滞术后神经损伤复杂且多因素。本文探讨了其发生机制、病因和危险因素,并对神经损伤的预防进行了文献检索和总结。

最新发现

新兴技术如超声、注射压力监测器和周围神经阻滞用神经刺激器已纳入常规实践,以降低神经损伤的发生率。研究表明,避免神经内注射、限制局部麻醉药的浓度/容量以及适当的患者选择是限制神经阻滞不良后果的最重要可控因素。神经阻滞术后发生外周神经损伤并不常见,且常被手术操作、体位和潜在神经完整性所掩盖。尽管进行了充分的病史和体格检查,但潜在的神经完整性并不总是明显的。手术应激,独立于神经阻滞,可能会加重这些神经疾病过程,使术后神经损伤的诊断更加困难。手术团队预防神经损伤、注意体位以及避免神经内注射是最具循证医学证据的实践。

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