Department of Management, Policy, and Community Health, School of Public Health, University of Texas Health Science Center at Houston, Room RAS E927, Houston, TX, 77030, USA.
Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, 77030, USA.
AIDS Behav. 2024 Aug;28(8):2793-2803. doi: 10.1007/s10461-024-04369-0. Epub 2024 Jun 1.
Evaluating routine HIV testing and treatment and use of services for people who inject drugs (PWID) is critical to curb the ongoing HIV epidemic. We analyzed data from the 2018 National HIV Behavioral Surveillance of PWID aged 18 years or older, recruited using respondent-driven sampling and offered anonymous HIV testing after survey. We performed bivariate and multivariable analyses with log-linked Poisson regression of the generalized linear models to examine the associations between demographics and PWID service use, past-year HIV testing, and current antiretroviral therapy (ART) use. Among 10,311 HIV-negative PWID, 56% reported past-year HIV testing, and of the 553 HIV-positive PWID, 69% reported current ART use. Of the HIV-negative PWID, 64% (2874/4482) in drug treatment and 62% (3386/5440) who used syringe service programs (SSPs) reported past-year HIV testing. Among HIV-positive PWID, 75% (187/248) in drug treatment and 67% (200/298) SSP participants were on ART. In the adjusted multivariable model, past-year HIV testing was associated with drug use treatment (aPR 1.26, 95% CI 1.23-1.31) and SSP participation (aPR 1.19, 95% CI 1.13-1.26) among HIV-negative PWID. Current ART use was associated with drug use treatment (aPR 1.13, 95% CI 1.00-1.28) but the link was not significant probably due to small sample size. Findings support the expansion and improvement of PWID-targeted services, into comprehensive programs, including drug use treatment, SSP, and HIV testing and treatment.
评估常规 HIV 检测和治疗以及注射吸毒者(PWID)的服务利用情况对于遏制持续的 HIV 流行至关重要。我们分析了 2018 年使用应答驱动抽样招募的年龄在 18 岁及以上的 PWID 国家 HIV 行为监测数据,并在调查后提供匿名 HIV 检测。我们使用广义线性模型的对数链接泊松回归进行了双变量和多变量分析,以检查人口统计学特征与 PWID 服务利用、过去一年的 HIV 检测和当前抗逆转录病毒治疗(ART)使用之间的关联。在 10311 名 HIV 阴性的 PWID 中,56%报告过去一年进行了 HIV 检测,在 553 名 HIV 阳性的 PWID 中,69%报告目前正在接受 ART 治疗。在 HIV 阴性的 PWID 中,64%(2874/4482)正在接受药物治疗,62%(3386/5440)使用过注射器服务项目(SSP)的人报告过去一年进行了 HIV 检测。在 HIV 阳性的 PWID 中,75%(187/248)正在接受药物治疗,67%(200/298)的 SSP 参与者正在接受 ART 治疗。在调整后的多变量模型中,过去一年的 HIV 检测与 HIV 阴性 PWID 的药物使用治疗(aPR 1.26,95%CI 1.23-1.31)和 SSP 参与(aPR 1.19,95%CI 1.13-1.26)相关。当前的 ART 使用与药物使用治疗(aPR 1.13,95%CI 1.00-1.28)相关,但由于样本量小,这种关联可能不显著。研究结果支持扩大和改善针对 PWID 的服务,将其纳入包括药物使用治疗、SSP 以及 HIV 检测和治疗在内的综合方案。
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