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从水果废料中提取抗菌治疗蛋白及其在抗感染方面的最新利用趋势。

Antimicrobial therapeutic protein extraction from fruit waste and recent trends in their utilization against infections.

机构信息

Department of Biotechnology, National Institute of Technology, Raipur, Chhattisgarh, 492010, India.

Department of Chemical Engineering, National Institute of Technology, Raipur, Chhattisgarh, 492010, India.

出版信息

Bioprocess Biosyst Eng. 2024 Nov;47(11):1767-1775. doi: 10.1007/s00449-024-03037-w. Epub 2024 May 31.

Abstract

Fruits are a very good source of various nutrients that can boost overall human health. In these days, the recovery of therapeutic compounds from different fruit wastes is trending in research, which might not only minimize the waste problem but also encounter a higher demand for various enzymes that could have antimicrobial properties against infectious diseases. The goal of this review is to focus on the recovery of therapeutic enzymes from fruit wastes and its present-day tendency for utilization. Here we discussed different parts of fruit waste, such as pulp, pomace, seed, kernel, peel, etc., that produce therapeutic enzymes like amylase, cellulose, lipase, laccase, pectinase, etc. These bioactive enzymes are present in different parts of fruit and could be used as therapeutics against various infectious diseases. This article provides a thorough knowledge compilation of therapeutic enzyme isolation from fruit waste on a single platform, distinctly informative, and significant review work on the topic that is envisioned to encourage further research ideas in these areas that are still under-explored. This paper explains the various aspects of enzyme isolation from fruit and vegetable waste and their biotherapeutic potential that could provide new insights into the development of biotherapeutics and attract the attention of researchers to enhance translational research magnitude further.

摘要

水果是各种营养物质的极好来源,这些营养物质可以促进整体人类健康。在当今时代,从各种水果废物中回收治疗化合物的研究正在兴起,这不仅可以最大限度地减少废物问题,还可以满足对具有抗菌性能的各种酶的更高需求,这些酶可以对抗传染病。本综述的目的是重点关注从水果废物中回收治疗酶及其当今的利用趋势。在这里,我们讨论了水果废物的不同部分,如果肉、果渣、种子、核仁、果皮等,这些部分可以产生治疗酶,如淀粉酶、纤维素酶、脂肪酶、漆酶、果胶酶等。这些生物活性酶存在于水果的不同部位,可以用作治疗各种传染病的药物。本文在一个单一的平台上提供了从水果废物中分离治疗酶的全面知识汇编,这是对该主题的非常有意义和重要的综述工作,预计将鼓励在这些仍未得到充分探索的领域进一步开展研究工作。本文解释了从水果和蔬菜废物中分离酶及其生物治疗潜力的各个方面,这可能为生物治疗药物的开发提供新的见解,并引起研究人员的关注,以进一步提高转化研究的规模。

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