Division of Cardiology, Department of Medicine, Nihon University School of Medicine.
Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine.
Int Heart J. 2024;65(3):586-590. doi: 10.1536/ihj.23-559.
Cholesterol crystal (CC) embolism is a disease in which CCs from atherosclerotic lesions embolize peripheral arteries, causing organ dysfunction. In this case, a patient with spontaneously ruptured aortic plaques (SRAPs) identified by non-obstructive general angioscopy (NOGA) may have developed a CC embolism. This is the first report of a CC embolism in a patient with SRAPs identified using NOGA, which further supports the previously speculated pathogenesis of CC embolism due to SRAPs.
胆固醇结晶(CC)栓塞是一种疾病,其中来自动脉粥样硬化病变的 CC 栓塞外周动脉,导致器官功能障碍。在这种情况下,通过非阻塞性全血管镜(NOGA)识别的自发性破裂主动脉斑块(SRAP)患者可能发生了 CC 栓塞。这是首例使用 NOGA 识别的 SRAP 患者发生 CC 栓塞的报告,进一步支持了先前推测的由于 SRAP 导致 CC 栓塞的发病机制。