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颈椎后路椎板切除术后颈椎后凸畸形伴或不伴融合。

Cervical kyphosis after posterior cervical laminectomy with and without fusion.

机构信息

Department of Orthopedics, University Spine Center Zurich, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.

Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Canada.

出版信息

Eur Spine J. 2024 Aug;33(8):3109-3116. doi: 10.1007/s00586-024-08260-3. Epub 2024 Jun 2.

Abstract

BACKGROUND

Cervical posterior instrumentation and fusion is often performed to avoid post-laminectomy kyphosis. However, larger comparative analyses of cervical laminectomy with or without fusion are sparse.

METHODS

A retrospective, two-center, comparative cohort study included patients after stand-alone dorsal laminectomy with (n = 91) or without (n = 46) additional fusion for degenerative cervical myelopathy with a median follow-up of 59 (interquartile range (IQR) 52) months. The primary outcome was the C2-7 Cobb angle and secondary outcomes were Neck Disability Index (NDI), modified Japanese Orthopaedic Association (mJOA) scale, revision rates, T1 slope and C2-7 sagittal vertical axis (C2-7 SVA) at final follow-up. Logistic regression analysis adjusted for potential confounders (i.e. age, operated levels, and follow-up).

RESULTS

Preoperative C2-7 Cobb angle and T1 slope were higher in the laminectomy group, while the C2-7 SVA was similar. The decrease in C2-7 Cobb angle from pre- to postoperatively was more pronounced in the laminectomy group (- 6° (IQR 20) versus -1° (IQR 7), p = 0.002). When adjusting for confounders, the decrease in C2-7 Cobb angle remained higher in the laminectomy group (coefficient - 12 (95% confidence interval (CI) -18 to -5), p = 0.001). However, there were no adjusted differences for postoperative NDI (- 11 (- 23 to 2), p = 0.10), mJOA, revision rates, T1 slope and C2-7 SVA.

CONCLUSION

Posterior cervical laminectomy without fusion is associated with mild loss of cervical lordosis of around 6° in the mid-term after approximately five years, however without any clinical relevance regarding NDI or mJOA in well-selected patients (particularly in shorter segment laminectomies of < 3 levels).

摘要

背景

颈椎后路内固定融合术常用于避免术后颈椎后凸畸形。然而,对于颈椎后路减压融合术与单纯减压术的大型对比分析较为少见。

方法

本回顾性、双中心、对比队列研究纳入了 91 例行单纯后路椎板切除术(融合组)和 46 例单纯后路椎板切除术(未融合组)治疗退行性颈椎病患者的资料,随访中位数为 59(四分位距 52)个月。主要结局为 C2-7 Cobb 角,次要结局为颈部残疾指数(NDI)、改良日本骨科协会(mJOA)评分、翻修率、T1 斜率和 C2-7 矢状垂直轴(C2-7 SVA)。采用多因素逻辑回归分析调整潜在混杂因素(年龄、手术节段和随访时间)。

结果

术前 C2-7 Cobb 角和 T1 斜率在减压组更高,而 C2-7 SVA 相似。减压组术后 C2-7 Cobb 角的下降更为明显(-6°(IQR 20)与-1°(IQR 7),p=0.002)。校正混杂因素后,减压组 C2-7 Cobb 角的下降仍较高(-12 度(95%置信区间-18 至-5),p=0.001)。然而,术后 NDI(-11 分(-23 至 2),p=0.10)、mJOA、翻修率、T1 斜率和 C2-7 SVA 无差异。

结论

在大约 5 年的中期随访中,后路颈椎单纯减压术不融合与颈椎前凸丢失约 6°相关,但在选择合适的患者(尤其是 3 个节段以下的短节段减压术)中,对 NDI 或 mJOA 无临床意义。

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