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一项混合方法的个体权衡(PTO)和定性研究的基本原理、概念问题及相应方案,旨在评估和了解儿童和年轻人与成年人相比健康收益的相对价值。

Rationale, conceptual issues, and resultant protocol for a mixed methods Person Trade Off (PTO) and qualitative study to estimate and understand the relative value of gains in health for children and young people compared to adults.

机构信息

Health Economics Unit, Centre for Health Policy, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.

Division of Population Health, School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom.

出版信息

PLoS One. 2024 Jun 3;19(6):e0302886. doi: 10.1371/journal.pone.0302886. eCollection 2024.

Abstract

BACKGROUND

Economic evaluation of healthcare typically assumes that an identical health gain to different patients has the same social value. There is some evidence that the public may give greater value to gains for children and young people, although this evidence is not always consistent. We present a mixed methods study protocol where we aim to explore public preferences regarding health gains to children and young people relative to adults, in an Australian setting.

METHODS

This study is a Person Trade Off (PTO) choice experiment that incorporates qualitative components. Within the PTO questions, respondents will be asked to choose between treating different groups of patients that may differ in terms of patient characteristics and group size. PTO questions will be included in an online survey to explore respondent views on the relative value of health gains to different age groups in terms of extending life and improving different aspects of quality of life. The survey will also contain attitudinal questions to help understand the impact of question style upon reported preferences. Additionally, the study will test the impact of forcing respondents to express a preference between two groups compared with allowing them to report that the two groups are equivalent. One-to-one 'think aloud', semi-structured interviews will be conducted to explore a sub-sample of respondents' motivations and views in more detail. Focus groups will be conducted with members of the public to discuss the study findings and explore their views on the role of public preferences in health care prioritisation based on patient age.

DISCUSSION

Our planned study will provide valuable information to healthcare decision makers in Australia who may need to decide whether to pay more for health gains for children and young people compared with adults. Additionally, the methodological test of forcing respondent choice or allowing them to express equivalence will contribute towards developing best practice methods in PTO studies. The rationale for and advantages of the study approach and potential limitations are discussed in the protocol.

摘要

背景

医疗保健的经济评估通常假设,不同患者获得相同的健康收益具有相同的社会价值。有一些证据表明,公众可能会更重视儿童和年轻人的收益,尽管这些证据并不总是一致的。我们提出了一项混合方法研究方案,旨在探讨澳大利亚公众对儿童和年轻人健康收益相对于成年人的偏好。

方法

本研究是一项个人权衡(PTO)选择实验,包含定性部分。在 PTO 问题中,受访者将被要求在治疗不同患者群体之间做出选择,这些患者群体可能在患者特征和群体规模方面存在差异。PTO 问题将包含在在线调查中,以探讨受访者对不同年龄组健康收益的相对价值的看法,这些健康收益涉及延长寿命和改善生活质量的不同方面。该调查还将包含态度问题,以帮助理解问题风格对报告偏好的影响。此外,该研究将测试在要求受访者在两组之间表达偏好与允许他们报告两组等效之间的偏好影响。将进行一对一的“出声思考”半结构化访谈,以更详细地探讨受访者的动机和观点。将对公众成员进行焦点小组讨论,以讨论研究结果,并探讨他们对基于患者年龄的公众偏好在医疗保健优先级排序中的作用的看法。

讨论

我们计划的研究将为澳大利亚的医疗保健决策者提供有价值的信息,决策者可能需要决定是否为儿童和年轻人的健康收益支付更多费用,而不是为成年人支付。此外,对强制受访者选择或允许他们表达等效性的方法进行测试,将有助于发展 PTO 研究中的最佳实践方法。方案中讨论了研究方法的理由、优势和潜在局限性。

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