Department of Urology, Shanghai Ruijin Hospital Zhoushan Branch, 316000 Zhoushan, Zhejiang, China.
Department of Gynecology, Shanghai Ruijin Hospital Zhoushan Branch, 316000 Zhoushan, Zhejiang, China.
Arch Esp Urol. 2024 May;77(4):385-390. doi: 10.56434/j.arch.esp.urol.20247704.52.
Urinary incontinence is common in patients with genitourinary syndrome of menopause (GSM). A retrospective cohort study was conducted to analyse the clinical efficacy of carbon dioxide laser combined with pelvic floor functional exercise for GSM with urinary incontinence, aiming to provide evidence for its clinical treatment.
Patients diagnosed with GSM and urinary incontinence and admitted to our hospital from January 2021 to December 2022 were included and allocated to a control group (pelvic floor function exercise) and combined group (carbon dioxide laser combined with pelvic floor function exercise). Confounding factors among the groups were balanced by the propensity score matching method. The clinical efficacy, GSM scale scores, urinary indicators, urinary incontinence quality of life scale (I-QOL) scores and the degree of urinary incontinence of the groups were compared.
A total of 192 patients were included in this study, and 36 cases were included in each group after the propensity scores were matched. No statistical difference in baseline data was found between the groups ( > 0.05). The combined group had higher total effective rate and I-QOL scores but lower GSM symptom scale scores than the control group. Urination during daytime and nighttime was less frequent in the combined group than in the control group, which showed a lower degree of urinary incontinence ( < 0.05).
Combining carbon dioxide laser treatment with pelvic floor exercises is potentially effective for patients with GSM and urinary incontinence. This combined approach not only alleviated GSM and urinary incontinence symptoms but also reduced the severity of urinary incontinence, promoted bladder function recovery and enhanced overall quality of life.
尿失禁是女性生殖泌尿系统综合征(GSM)患者的常见症状。本回顾性队列研究旨在分析二氧化碳激光联合盆底功能锻炼治疗 GSM 合并尿失禁的临床疗效,为其临床治疗提供依据。
选取 2021 年 1 月至 2022 年 12 月在我院诊断为 GSM 合并尿失禁的患者,采用倾向性评分匹配法将其分为对照组(盆底功能锻炼)和联合组(二氧化碳激光联合盆底功能锻炼)。比较两组患者的临床疗效、GSM 量表评分、尿动力学指标、尿失禁生活质量量表(I-QOL)评分和尿失禁程度。
共纳入 192 例患者,经倾向性评分匹配后每组 36 例。两组患者的基线资料比较,差异无统计学意义(>0.05)。联合组总有效率和 I-QOL 评分均高于对照组,GSM 症状量表评分低于对照组;联合组日间和夜间排尿次数少于对照组,尿失禁程度低于对照组,差异均有统计学意义(<0.05)。
二氧化碳激光联合盆底功能锻炼治疗 GSM 合并尿失禁疗效确切,可改善 GSM 及尿失禁症状,降低尿失禁程度,促进膀胱功能恢复,提高患者生活质量。