Salikhanov Islam, Koechlin Luca, Gahl Brigitta, Reuthebuch Oliver, Zellweger Michael, Haaf Philip, Bremerich Jens, Pradella Maurice, Müller Christian, Berdajs Denis
Department of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Department of Cardiology, University Hospital Basel, Basel, Switzerland.
Front Cardiovasc Med. 2024 May 23;11:1400637. doi: 10.3389/fcvm.2024.1400637. eCollection 2024.
To evaluate incidence and predictors of early silent bypass occlusion following coronary bypass surgery using cardiac computed tomography angiography.
A total of 439 consecutive patients with mean age of 66 ± 10 years comprising 17% ( = 75) females underwent isolated coronary bypass surgery followed by CT scan before discharge. Graft patency was evaluated in 1,319 anastomoses where 44% ( = 580) arterial and 56% ( = 739) vein graft anastomosis were performed. Cardiovascular risk factors, demographics, and intraoperative variables were analyzed. We conducted univariable and multivariable logistic regression analyses to analyze variables potentially associated with graft occlusion following CABG. Variables included gender, surgery duration, graft flow, pulsatility index, vein vs. artery graft, and recent MI.
Overall incidence of graft occlusion was 2.4% (31/1,319), and it was diagnosed in 6.6% (29/439) of patients. The difference in occlusion between arterial (2.1%) and vein (2.6%) grafts was not significant, = 0.68. The duration of intervention = 0.034, cross clamp time = 0.024 as well the number of distal anastomosis = 0.034 were significantly higher in occlusion group. The univariate and multivariate logistic regression indicated duration of surgery being predictive for bypass graft occlusion with OR = 1.18; 95% CI: 1.01-1.38; = 0.035.
Early graft occlusion was associated with surgical factors. The number of distant anastamoses, along duration of surgical intervention were, significantly influenced the risk of EGO. Prolonged procedural time reflecting complex coronary pathology and time-consuming revascularization procedure was as well associated to the elevated risk of occlusion.
使用心脏计算机断层扫描血管造影术评估冠状动脉搭桥手术后早期无症状搭桥血管闭塞的发生率及预测因素。
连续纳入439例平均年龄为66±10岁的患者,其中17%(n = 75)为女性,均接受了单纯冠状动脉搭桥手术,并在出院前行CT扫描。对1319处吻合口的移植血管通畅情况进行评估,其中动脉吻合口44%(n = 580),静脉吻合口56%(n = 739)。分析心血管危险因素、人口统计学特征及术中变量。我们进行了单变量和多变量逻辑回归分析,以分析与冠状动脉搭桥术后移植血管闭塞可能相关的变量。变量包括性别、手术时间、移植血管血流、搏动指数、静脉与动脉移植血管、近期心肌梗死。
移植血管闭塞的总体发生率为2.4%(31/1319),在6.6%(29/439)的患者中被诊断出。动脉移植血管(2.1%)和静脉移植血管(2.6%)闭塞率的差异不显著,P = 0.68。干预时间(P = 0.034)、交叉钳夹时间(P = 0.024)以及远端吻合口数量(P = 0.034)在闭塞组中显著更高。单变量和多变量逻辑回归表明手术时间可预测搭桥血管闭塞,OR = 1.18;95%CI:1.01 - 1.38;P = 0.035。
早期移植血管闭塞与手术因素相关。远端吻合口数量以及手术干预时间显著影响早期移植血管闭塞的风险。反映复杂冠状动脉病变和耗时血运重建过程的手术时间延长也与闭塞风险升高相关。