初始血清 25-羟维生素 D 与糖尿病足溃疡肉芽生长的相关性。
Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers.
机构信息
Division of Endocrinology, Metabolism, and Diabetes, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
出版信息
J Wound Care. 2024 Jun 1;33(Sup6a):clii-clix. doi: 10.12968/jowc.2021.0243.
OBJECTIVE
To determine the correlation between initial serum 25-hydroxyvitamin D (25(OH)D) levels with granulation growth in diabetic foot ulcers (DFUs) after 21 days of treatment.
METHOD
This cohort study involved patients with type 2 diabetes who had a DFU treated at hospital. Blood samples were taken from patients on admission. The chemiluminescent immunoassay technique was used to measure 25(OH)D levels. Granulation tissue growth was analysed by comparing the photographs from the initial treatment to day 21 of treatment.
RESULTS
The median value of 25(OH)D levels at initial treatment was 8 ng/ml. The result showed no correlation between 25(OH)D levels and the granulation growth in DFUs (p=0.86).
CONCLUSION
The initial serum 25(OH)D level was not correlated with the growth of granulation tissue in DFUs.
目的
确定治疗 21 天后初始血清 25-羟维生素 D（25（OH）D）水平与糖尿病足溃疡（DFU）肉芽生长之间的相关性。
方法
本队列研究纳入了在医院接受治疗的 2 型糖尿病合并 DFU 的患者。入院时采集患者的血样。采用化学发光免疫分析法测定 25（OH）D 水平。通过比较初始治疗和治疗第 21 天的照片来分析肉芽组织的生长情况。
结果
初始治疗时 25（OH）D 水平的中位数为 8ng/ml。结果显示，25（OH）D 水平与 DFU 中的肉芽生长之间无相关性（p=0.86）。
结论
初始血清 25（OH）D 水平与 DFU 中肉芽组织的生长无关。
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