Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, The Netherlands.
Danone Nutricia Research, Utrecht, The Netherlands.
Arch Phys Med Rehabil. 2024 Oct;105(10):1854-1861. doi: 10.1016/j.apmr.2024.05.021. Epub 2024 Jun 6.
To determine the prevalence and co-occurrence of common geriatric syndromes in geriatric rehabilitation inpatients.
Restoring Health of Acutely Unwell Adults (RESORT) and Enhancing Muscle Power in Geriatric Rehabilitation (EMPOWER-GR) are observational, longitudinal cohorts.
Geriatric rehabilitation.
Geriatric rehabilitation inpatients (N=1890 and N=200).
Not applicable.
Geriatric syndromes included polypharmacy, multimorbidity (Cumulative Illness Rating Scale), cognitive impairment, depression (Hospital Anxiety and Depression Scale/Geriatric Depression Scale), malnutrition (Global Leadership Initiative on Malnutrition), functional limitation (Katz index), falls, physical frailty (Fried), and sarcopenia (European Working Group on Sarcopenia in Older People 2).
Inpatients in RESORT (R) (N=1890, 56% females) had a median age of 83.4 years (interquartile range [IQR], 77.6-88.4) and in EMPOWER-GR (E) (N=200, 57% females) of 79.8 years (IQR, 75.0-85.9). Polypharmacy (R, 82.2%; E, 84.0%), multimorbidity (R, 90.4%; E, 85.5%), functional limitation (R, 96.0%; E, 76.5%), and frailty (R, 91.8%; E, 92.2%) were most prevalent. Most inpatients had ≥5 geriatric syndromes at admission in both cohorts (R, 70.0%; E, 72.4%); few inpatients had only 1 (R, 0.4%; E, 1.5%) or no geriatric syndrome (R, 0.2%; E, 0.0%). Geriatric syndromes did not occur in isolation (without other syndromes), except for multimorbidity (R, 1%; E, 5%), functional limitation (R, 3%; E, 2%), falls (R, 0%; E, 4%), and frailty (R, 2%; E, 5%), which occurred in isolation in some inpatients; sarcopenia did not.
Geriatric syndromes are highly prevalent at admission to geriatric rehabilitation, with a median of 5 co-occurring syndromes. Implications for diagnosis and intervention potential should be further addressed.
确定老年康复住院患者常见老年综合征的患病率和共病情况。
康复成人健康恢复研究（RESORT）和增强老年康复肌肉力量研究（EMPOWER-GR）为观察性、纵向队列研究。
老年康复。
老年康复住院患者（RESORT 组 N=1890，EMPOWER-GR 组 N=200）。
无。
老年综合征包括多重用药（累积疾病评分量表）、多种合并症（累积疾病评分量表）、认知障碍（医院焦虑抑郁量表/老年抑郁量表）、营养不良（全球营养领导倡议）、功能受限（Katz 指数）、跌倒、身体虚弱（Fried）和肌少症（欧洲老年人肌少症工作组 2 型）。
RESORT 组（R）（N=1890，56%女性）的中位年龄为 83.4 岁（四分位间距[IQR]，77.6-88.4），EMPOWER-GR 组（E）（N=200，57%女性）的中位年龄为 79.8 岁（IQR，75.0-85.9）。多重用药（R 组 82.2%；E 组 84.0%）、多种合并症（R 组 90.4%；E 组 85.5%）、功能受限（R 组 96.0%；E 组 76.5%）和虚弱（R 组 91.8%；E 组 92.2%）最为常见。两个队列中大多数住院患者入院时均有≥5 种老年综合征（R 组 70.0%；E 组 72.4%）；只有少数患者（R 组 0.4%；E 组 1.5%）或无老年综合征（R 组 0.2%；E 组 0.0%）。除了多种合并症（R 组 1%；E 组 5%）、功能受限（R 组 3%；E 组 2%）、跌倒（R 组 0%；E 组 4%）和虚弱（R 组 2%；E 组 5%）外，老年综合征不会单独发生（没有其他综合征），肌少症除外。
老年康复住院患者入院时老年综合征高度普遍，平均有 5 种共病。应进一步探讨诊断和干预潜力的意义。
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