Suppr超能文献

银屑病转化为皮肤 T 细胞淋巴瘤 1 例报告。

CASE OF THE TRANSFORMATION OF PSORIASIS INTO CUTANEOUS T-CELL LYMPHOMA.

机构信息

Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.

Municipal Institution «Precarpathian Clinical Dermatological and Venereological Center of Ivano-Frankivsk Regional Council», Ivano-Frankivsk, Ukraine.

出版信息

Exp Oncol. 2024 May 31;46(1):68-71. doi: 10.15407/exp-oncology.2024.01.068.

Abstract

Psoriasis is a long-known skin pathology, the incidence of which is constantly rising, though it is not possible to clearly establish the trend due to the differences in the research design. In recent years, the number of cases among children and adolescents has increased. Psoriasis becomes more aggressive, severe forms are more common. It can be combined with other diseases but is rarely complicated. Isolated cases of the transformation of psoriatic plaques into skin cancer have already been described in the literature. Probable causes were the long-term use of photosensitizers and phototherapy, naphthalene, and tar. However, in general, the risk of the malignant recurrence in patients with psoriasis does not increase significantly. We present a clinical observation of the transformation of psoriasis into cutaneous T-cell lymphoma in a patient with more than 37 years of psoriasis experience, where on the background of typical psoriatic rashes, fungal growths of doughy consistency appeared, which were initially misinterpreted as a warty form of psoriasis. Based on the data of additional methods of examination and the results of histological examination, the diagnosis was clarified. Specific treatment was prescribed, which proved its effectiveness. The probable causes of degeneration, in our opinion, are prolonged irritating external therapy and excessive insolation.

摘要

银屑病是一种由来已久的皮肤病理学,其发病率不断上升,但由于研究设计的差异,无法明确其趋势。近年来,儿童和青少年的病例数量有所增加。银屑病变得更加严重,更常见严重的形式。它可能与其他疾病同时发生,但很少出现并发症。孤立的银屑病斑块转化为皮肤癌的病例在文献中已有描述。可能的原因是长期使用光敏剂和光疗、萘和焦油。然而,一般来说,银屑病患者的恶性复发风险并没有显著增加。我们报告了一例 37 年以上银屑病病史的患者,其银屑病转化为皮肤 T 细胞淋巴瘤的临床观察。在典型的银屑病皮疹背景下,出现了面团状的真菌生长,最初被误诊为疣状银屑病。基于额外检查方法的数据和组织学检查结果,明确了诊断。开出了特定的治疗方法,证明了其有效性。我们认为,退化的可能原因是长期刺激性的外部治疗和过度日晒。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验