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Clinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter.

作者信息

Lefaucheur Jean-Pascal, Moro Elena, Shirota Yuichiro, Ugawa Yoshikazu, Grippe Talyta, Chen Robert, Benninger David H, Jabbari Bahman, Attaripour Sanaz, Hallett Mark, Paulus Walter

机构信息

Clinical Neurophysiology Unit, Henri Mondor University Hospital, AP-HP, Créteil, France; EA 4391, ENT Team, Paris-Est Créteil University, Créteil, France.

Grenoble Alpes University, Division of Neurology, CHU of Grenoble, Grenoble Institute of Neuroscience, Grenoble, France.

出版信息

Clin Neurophysiol. 2024 Aug;164:57-99. doi: 10.1016/j.clinph.2024.05.007. Epub 2024 May 23.


DOI:10.1016/j.clinph.2024.05.007
PMID:38852434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11418354/
Abstract

In this review, different aspects of the use of clinical neurophysiology techniques for the treatment of movement disorders are addressed. First of all, these techniques can be used to guide neuromodulation techniques or to perform therapeutic neuromodulation as such. Neuromodulation includes invasive techniques based on the surgical implantation of electrodes and a pulse generator, such as deep brain stimulation (DBS) or spinal cord stimulation (SCS) on the one hand, and non-invasive techniques aimed at modulating or even lesioning neural structures by transcranial application. Movement disorders are one of the main areas of indication for the various neuromodulation techniques. This review focuses on the following techniques: DBS, repetitive transcranial magnetic stimulation (rTMS), low-intensity transcranial electrical stimulation, including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), and focused ultrasound (FUS), including high-intensity magnetic resonance-guided FUS (MRgFUS), and pulsed mode low-intensity transcranial FUS stimulation (TUS). The main clinical conditions in which neuromodulation has proven its efficacy are Parkinson's disease, dystonia, and essential tremor, mainly using DBS or MRgFUS. There is also some evidence for Tourette syndrome (DBS), Huntington's disease (DBS), cerebellar ataxia (tDCS), and axial signs (SCS) and depression (rTMS) in PD. The development of non-invasive transcranial neuromodulation techniques is limited by the short-term clinical impact of these techniques, especially rTMS, in the context of very chronic diseases. However, at-home use (tDCS) or current advances in the design of closed-loop stimulation (tACS) may open new perspectives for the application of these techniques in patients, favored by their easier use and lower rate of adverse effects compared to invasive or lesioning methods. Finally, this review summarizes the evidence for keeping the use of electromyography to optimize the identification of muscles to be treated with botulinum toxin injection, which is indicated and widely performed for the treatment of various movement disorders.

摘要

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本文引用的文献

[1]
Plasticity-Induced Effects of Theta Burst Transcranial Ultrasound Stimulation in Parkinson's Disease.

Mov Disord. 2024-8

[2]
The history of deep brain stimulation.

Parkinsonism Relat Disord. 2024-4

[3]
Electrophysiological evaluation of the neuromuscular junction: a brief review.

Arq Neuropsiquiatr. 2023-12

[4]
Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson's disease.

Transl Neurodegener. 2023-11-30

[5]
Deep brain stimulation for essential tremor versus essential tremor plus: should we target the same spot in the thalamus?

Front Hum Neurosci. 2023-10-31

[6]
Are patients with GBA-Parkinson disease good candidates for deep brain stimulation? A longitudinal multicentric study on a large Italian cohort.

J Neurol Neurosurg Psychiatry. 2024-3-13

[7]
The Challenge of Choosing the Right Stimulation Target for Dystonic Tremor-A Series of Instructive Cases.

Mov Disord Clin Pract. 2023-8-22

[8]
Accelerated Transcranial Ultrasound Neuromodulation in Parkinson's Disease: A Pilot Study.

Mov Disord. 2023-12

[9]
Transcranial focused ultrasound-mediated neurochemical and functional connectivity changes in deep cortical regions in humans.

Nat Commun. 2023-9-1

[10]
Deep brain stimulation in multiple sclerosis-associated tremor. A large, retrospective, longitudinal open label study, with long-term follow-up.

Mult Scler Relat Disord. 2023-11

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