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用于实现具有任意输入偏振态的深度分辨全光纤偏振敏感光学相干断层扫描的数字校准方法。

Digital calibration method to enable depth-resolved all-fiber polarization sensitive optical coherence tomography with an arbitrary input polarization state.

作者信息

Tang Peijun, Wang Ruikang K, Chao Qing

机构信息

Department of Bioengineering, University of Washington, 3720 15th Ave NE, Seattle, Washington 98195, USA.

Department of Ophthalmology, University of Washington, 750 Republican St., Seattle, Washington 98195, USA.

出版信息

Biomed Opt Express. 2024 Apr 24;15(5):3329-3343. doi: 10.1364/BOE.517826. eCollection 2024 May 1.

Abstract

We present a fully integrated depth-resolved all fiber-based polarization sensitive optical coherence tomography (PSOCT). In contrast to conventional fiber-based PSOCT systems, which require additional modules to generate two or more input polarization states, or a pre-adjustment procedure to generate a circularly polarized light, the proposed all-fiber PSOCT system can provide depth-resolved birefringent imaging using an arbitrary single input polarization state. Utilizing the discrete differential geometry (DDG)-based polarization state tracing (PST) method, combined with several geometric rotations and transformations in the Stokes space, two problems induced by the optical fibers can be mitigated: 1) The change in the polarization state introduced by the optical fibers can be effectively compensated using a calibration target at the distal end of the probe, and the computations of the local axis orientation and local phase retardation can be achieved with a single arbitrary input polarization state, eliminating the need for a pre-defined input polarization state, allowing a flexible system design and user-friendly experimental procedure; 2) The polarization mode dispersion (PMD) induced by the optical fibers can be compensated digitally without the requirement of additional input polarization states, providing an accurate PSOCT imaging result. To demonstrate the performance of the proposed method, the depth resolved PSOCT results of a plastic phantom and skin imaging are obtained using the proposed all-fiber PSOCT system.

摘要

我们展示了一种完全集成的深度分辨全光纤偏振敏感光学相干断层扫描(PSOCT)。与传统的基于光纤的PSOCT系统不同,传统系统需要额外的模块来生成两个或更多输入偏振态,或者需要一个预调整程序来生成圆偏振光,而本文提出的全光纤PSOCT系统可以使用任意单个输入偏振态提供深度分辨双折射成像。利用基于离散微分几何(DDG)的偏振态追踪(PST)方法,结合斯托克斯空间中的几种几何旋转和变换,可以减轻光纤引起的两个问题:1)使用探头远端的校准目标可以有效补偿光纤引入的偏振态变化,并且可以通过单个任意输入偏振态实现局部轴方向和局部相位延迟的计算,无需预定义输入偏振态,从而实现灵活的系统设计和用户友好的实验过程;2)光纤引起的偏振模色散(PMD)可以在不需要额外输入偏振态的情况下进行数字补偿,从而提供准确的PSOCT成像结果。为了证明所提方法的性能,使用所提出的全光纤PSOCT系统获得了塑料模型的深度分辨PSOCT结果和皮肤成像结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a36/11161387/a41c82e7792e/boe-15-5-3329-g001.jpg

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