White J M, Nowak R M, Martin G B, Best R, Carden D L, Tomlanovich M C
Ann Emerg Med. 1985 Apr;14(4):298-302. doi: 10.1016/s0196-0644(85)80090-1.
Approximately 25% of patients in prehospital cardiac arrest present in bradyasystolic rhythms, and their long-term prognosis is very poor. Our study was undertaken to determine the utility of immediate emergency department (ED) external cardiac pacing in this situation. Twenty patients presenting with bradyasystolic prehospital cardiac arrest were entered in the study. All received the usual advanced cardiac life support therapy, but also were externally paced immediately using an automated external defibrillator and pacemaker (AEDP). Only two of 20 patients showed evidence of electrical capture, and none developed pulses with pacing. Four of the 20 patients developed a sinus rhythm and blood pressure during resuscitation. Three survived to leave the ED, but none survived to leave the hospital. An increase in the rate of bradycardia and pulseless idioventricular rhythms that was independent of electrical capture or pharmacologic therapy was noted occasionally. Although survival was not enhanced using the AEDP, the device was reliable, easy to use, and free of complications. External cardiac pacing warrants further investigation in the prehospital setting.
大约25%的院外心脏骤停患者表现为缓慢性心搏停止节律,其长期预后非常差。我们开展这项研究以确定在这种情况下急诊室立即进行体外心脏起搏的效用。20例表现为缓慢性心搏停止院外心脏骤停的患者进入该研究。所有患者均接受了常规的高级心脏生命支持治疗,但也立即使用自动体外除颤器和起搏器(AEDP)进行体外起搏。20例患者中只有2例显示有电捕获证据,且无一例通过起搏产生脉搏。20例患者中有4例在复苏过程中出现窦性心律和血压。3例存活至离开急诊室,但无一例存活至出院。偶尔会注意到与电捕获或药物治疗无关的心动过缓和无脉性室性逸搏心律发生率增加。虽然使用AEDP并未提高生存率,但该设备可靠、易于使用且无并发症。体外心脏起搏在院外环境中值得进一步研究。