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撒哈拉以南非洲地区卒中幸存者卒中后认知功能下降的预测因素:系统评价和荟萃分析。

Predictors of Poststroke Cognitive Decline among Stroke Survivors in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.

机构信息

Department of Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Department of Maternity and Neonatal Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

出版信息

Dement Geriatr Cogn Disord. 2024;53(5):265-273. doi: 10.1159/000539449. Epub 2024 Jun 13.

DOI:10.1159/000539449
PMID:38870910
Abstract

INTRODUCTION

Stroke is a devastating medical disorder associated with significant morbidity and mortality among adults and the elderly worldwide. Although numerous primary studies have been conducted to determine the pooled predictors of poststroke cognitive decline among stroke survivors in Sub-Saharan Africa, these studies presented inconsistent findings. Hence, the review aimed to determine the pooled predictors of poststroke cognitive decline among stroke survivors in Sub-Saharan Africa.

METHODS

The eligible studies were accessed through Google Scholar, Scopus, PubMed, and Web of Science databases. A manual search of the reference lists of included studies was performed. A weighted inverse-variance random-effects model was used to determine the pooled predictors of poststroke cognitive decline among stroke survivors in Sub-Saharan Africa.

RESULTS

A total of 1,710 stroke survivors from 10 primary studies were included in the final meta-analysis. Increased age (≥45 years) (adjusted odds ratio [AOR] = 1.32, 95% CI: 1.13, 1.54), lower educational level (AOR = 4.58, 95% CI: 2.98, 7.03), poor functional recovery (AOR = 1.75, 95% CI: 1.42, 2.15), and left hemisphere stroke (AOR = 4.88, 95% CI: 2.98, 7.99) were significantly associated with poststroke cognitive decline.

CONCLUSIONS

Increased age, lower educational level, poor functional recovery, and left hemisphere stroke were the pooled independent predictors of poststroke cognitive decline in Sub-Saharan Africa Healthcare providers, and other concerned bodies should give attention to these risk factors as the early identification may help to improve the cognitive profile of stroke survivors.

摘要

简介

中风是一种严重的医学疾病,在全球范围内,成年人和老年人的发病率和死亡率都很高。尽管已经进行了许多初步研究,以确定撒哈拉以南非洲中风幸存者中风后认知能力下降的综合预测因素,但这些研究的结果并不一致。因此,本综述旨在确定撒哈拉以南非洲中风幸存者中风后认知能力下降的综合预测因素。

方法

通过 Google Scholar、Scopus、PubMed 和 Web of Science 数据库获取符合条件的研究。对纳入研究的参考文献进行了手动搜索。使用加权逆方差随机效应模型来确定撒哈拉以南非洲中风幸存者中风后认知能力下降的综合预测因素。

结果

共有 10 项初步研究的 1710 名中风幸存者纳入最终的荟萃分析。年龄较大(≥45 岁)(调整后的优势比 [AOR] = 1.32,95%可信区间:1.13,1.54)、教育程度较低(AOR = 4.58,95%可信区间:2.98,7.03)、功能恢复不良(AOR = 1.75,95%可信区间:1.42,2.15)和左半球中风(AOR = 4.88,95%可信区间:2.98,7.99)与中风后认知能力下降显著相关。

结论

年龄较大、教育程度较低、功能恢复不良和左半球中风是撒哈拉以南非洲中风后认知能力下降的综合独立预测因素。医疗保健提供者和其他相关机构应关注这些危险因素,因为早期识别可能有助于改善中风幸存者的认知状况。

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