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利用国际血液和骨髓移植研究中心的造血细胞移植数据和生物库资源改善患者预后。

Leveraging Hematopoietic Cell Transplant Data and Biorepository Resources at the Center for International Blood and Marrow Transplant Research to Improve Patient Outcomes.

机构信息

CIBMTR® (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota.

CIBMTR® (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin.

出版信息

Transplant Cell Ther. 2024 Sep;30(9):921.e1-921.e22. doi: 10.1016/j.jtct.2024.06.010. Epub 2024 Jun 11.

Abstract

Hematopoietic cell transplantation (HCT) has undergone many advances over the decades. Trends in HCT utilization have been impacted by research based on the data and samples collected by the Center for International Blood and Marrow Transplant Research (CIBMTR). Here, we provide a summary report of the CIBMTR Biorepository resource and describe the biospecimen inventory along with collection and request procedures. The diversity captured in this inventory reflects transplant activity, and these samples can be leveraged for secondary analyses to generate more data and insights to advance the field. We describe how our resources have already impacted HCT practice and elaborate on possibilities for further collaboration and utilization to maximize capabilities and research opportunities. Hematopoietic cell transplant data and biorepository resources at the CIBMTR have been and continue to be leveraged to improve patient outcomes.

摘要

造血细胞移植(HCT)在过去几十年中取得了许多进展。基于中心国际血液和骨髓移植研究(CIBMTR)收集的数据和样本进行的研究,影响了 HCT 的应用趋势。在这里,我们提供了 CIBMTR 生物库资源的总结报告,并描述了生物样本库的库存情况,以及收集和请求程序。该库存中捕获的多样性反映了移植活动,这些样本可用于二次分析,以生成更多的数据和见解,从而推动该领域的发展。我们描述了我们的资源如何已经影响 HCT 实践,并详细说明了进一步合作和利用的可能性,以最大限度地发挥能力和研究机会。CIBMTR 的造血细胞移植数据和生物库资源已经并将继续被利用来改善患者的预后。

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