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女性患者网状物相关尿道梗阻的单侧J形切开术与部分及次全切除术技术:多中心比较研究

Unilateral J-cut division versus partial and subtotal removal techniques in female patients with mesh-related urethral obstruction: Multicentric comparative study.

作者信息

Çetinel Bülent, Kalender Göktuğ, Kırlı Elif Altınay, Yenilmez Aydın, Gülpınar Ömer, Şimşir Adnan, Temeltaş Gökhan, Çubuk Alkan, Can Günay

机构信息

Cerrahpaşa Faculty of Medicine, Department of Urology Istanbul University-Cerrahpaşa Istanbul Turkey.

Faculty of Medicine, Department of Urology Eskişehir Osmangazi University Eskişehir Turkey.

出版信息

BJUI Compass. 2024 Mar 25;5(6):551-557. doi: 10.1002/bco2.350. eCollection 2024 Jun.

Abstract

OBJECTIVE

To compare the functional (obstruction relieving) outcomes and complications of unilateral J-cut division, partial and subtotal vaginal removal techniques were performed for mesh-related urethral obstruction (MRUO) in females.

METHODS

Patient review included demographics, a medical history and proforma with details of lower urinary tract symptoms (LUTS), physical and urodynamic findings, detailed surgical reports and follow-up data. Variables were compared between the three groups.

RESULTS

Out of 130 patients with sling revision surgery (SRS), 54 women underwent SRS for MRUO with a median follow-up of 48 (17-96) months. Unilateral J-cut division, partial and subtotal vaginal removal techniques were performed in 12, 31 and 11 patients with a median duration of surgery of 30 (25-34), 40 (35-56) and 60 (60-70) minutes, respectively ( = 0.001). Statistically significant increase in median maximum free urine flow rate and decrease in median post-void residual urine volume were found after SRS in the three groups, while de novo stress urinary incontinence (SUI) developed in 10%, 44% and 60% of the patients in the unilateral J-cut division, partial and subtotal removal groups, respectively ( = 0.007).

CONCLUSIONS

The unilateral J-cut division technique was as effective as the partial and subtotal vaginal removal techniques in relieving MRUO with a shorter duration of surgery time ( = 0.001) and lower risk of de novo SUI ( = 0.007). Comparative studies with a larger number of patients are needed.

摘要

目的

比较单侧J形切开分离术、部分阴道切除术和次全阴道切除术治疗女性网状物相关尿道梗阻(MRUO)的功能(梗阻缓解)结局及并发症。

方法

患者回顾包括人口统计学资料、病史以及包含下尿路症状(LUTS)详细信息、体格检查和尿动力学检查结果、详细手术报告及随访数据的表格。对三组之间的变量进行比较。

结果

在130例行吊带修复手术(SRS)的患者中,54例女性因MRUO接受了SRS,中位随访时间为48(17 - 96)个月。分别对12例、31例和11例患者实施了单侧J形切开分离术、部分阴道切除术和次全阴道切除术,手术中位时长分别为30(25 - 34)分钟、40(35 - 56)分钟和60(60 - 70)分钟(P = 0.001)。三组患者SRS术后中位最大自由尿流率均有统计学意义的显著增加,中位排尿后残余尿量均有下降,而单侧J形切开分离术组、部分切除术组和次全切除术组分别有10%、44%和60%的患者出现了新发压力性尿失禁(SUI)(P = 0.007)。

结论

单侧J形切开分离术在缓解MRUO方面与部分阴道切除术和次全阴道切除术同样有效,手术时间更短(P = 0.001),新发SUI风险更低(P = 0.007)。需要开展更多患者参与的对比研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f32b/11168769/fa6843624d9c/BCO2-5-551-g001.jpg

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