Yeom Arim, Yoo So-Young, Jeon Tae Yeon, Park Jieun, Kim Ji Hye
J Korean Soc Radiol. 2024 May;85(3):505-519. doi: 10.3348/jksr.2024.0039. Epub 2024 May 29.
MRI plays a crucial role in bone marrow (BM) assessment, and has very high sensitivity in diagnosing marrow disorders. However, for radiologists who may not frequently encounter pediatric imaging, distinguishing pathologic BM lesion from normal BM can be challenging. Conditions involving the BM in pediatric patients, such as leukemia and metastatic neuroblastoma, often manifest with diverse musculoskeletal symptoms and may be diagnosed using musculoskeletal MRI examinations. Accurate interpretation of pediatric MRI requires not only an understanding of the normal composition of BM but also an awareness of agerelated developmental changes in the marrow and familiarity with conditions that commonly involve pediatric BM. We aim to describe the composition of normal BM and outline the normal and abnormal MRI findings in pediatric BM. Additionally, we aim to present clinical cases of malignant BM disorders including leukemia, neuroblastoma metastasis, and other malignant BM disorders.
磁共振成像(MRI)在骨髓(BM)评估中起着至关重要的作用,并且在诊断骨髓疾病方面具有很高的敏感性。然而,对于可能不经常接触儿科影像的放射科医生来说,区分病理性骨髓病变与正常骨髓可能具有挑战性。儿科患者中涉及骨髓的疾病,如白血病和转移性神经母细胞瘤,通常表现为多样的肌肉骨骼症状,可通过肌肉骨骼MRI检查进行诊断。准确解读儿科MRI不仅需要了解骨髓的正常组成,还需要认识到骨髓中与年龄相关的发育变化,并熟悉常见累及儿科骨髓的疾病。我们旨在描述正常骨髓的组成,并概述儿科骨髓的正常和异常MRI表现。此外,我们旨在展示包括白血病、神经母细胞瘤转移和其他恶性骨髓疾病在内的恶性骨髓疾病的临床病例。