Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, 518107, China.
Department of Rehabilitation Medicine, The First Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510080, China.
J Neuroeng Rehabil. 2024 Jun 14;21(1):102. doi: 10.1186/s12984-024-01376-z.
Investigating the spatial distribution of muscle activity would facilitate understanding the underlying mechanism of spasticity. The purpose of this study is to investigate the characteristics of spastic muscles during passive stretch and active contraction by high-density surface electromyography (HD-sEMG).
Fourteen spastic hemiparetic subjects and ten healthy subjects were recruited. The biceps brachii (BB) muscle activity of each subject was recorded by HD-sEMG during passive stretch at four stretch velocities (10, 60, 120, 180˚/s) and active contraction at three submaximal contraction levels (20, 50, 80%MVC). The intensity and spatial distribution of the BB activity were compared by the means of two-way analysis of variance, independent sample t-test, and paired sample t-test.
Compared with healthy subjects, spastic hemiparetic subjects showed significantly higher intensity with velocity-dependent heterogeneous activation during passive stretch and more lateral and proximal activation distribution during active contraction. In addition, spastic hemiparetic subjects displayed almost non-overlapping activation areas during passive stretch and active contraction. The activation distribution of passive stretch was more distal when compared with the active contraction.
These alterations of the BB activity could be the consequence of deficits in the descending central control after stroke. The complementary spatial distribution of spastic BB activity reflected their opposite motor units (MUs) recruitment patterns between passive stretch and active contraction. This HD-sEMG study provides new neurophysiological evidence for the spatial relationship of spastic BB activity between passive stretch and active contraction, advancing our knowledge on the mechanism of spasticity.
ChiCTR2000032245.
研究肌肉活动的空间分布将有助于理解痉挛的潜在机制。本研究旨在通过高密度表面肌电图（HD-sEMG）研究痉挛性肌肉在被动拉伸和主动收缩过程中的特征。
招募了 14 名痉挛性偏瘫患者和 10 名健康受试者。通过 HD-sEMG 记录每位受试者的肱二头肌（BB）肌肉在 4 种拉伸速度（10、60、120、180°/s）下的被动拉伸和 3 种亚最大收缩水平（20、50、80%MVC）下的主动收缩过程中的活动。通过双因素方差分析、独立样本 t 检验和配对样本 t 检验比较 BB 活动的强度和空间分布。
与健康受试者相比，痉挛性偏瘫患者在被动拉伸时表现出明显更高的强度和速度依赖性异质性激活，在主动收缩时表现出更侧向和更近端的激活分布。此外，痉挛性偏瘫患者在被动拉伸和主动收缩期间显示出几乎不重叠的激活区域。与主动收缩相比，被动拉伸的激活分布更靠远端。
这些 BB 活动的改变可能是中风后下行中枢控制缺陷的结果。痉挛性 BB 活动的补充空间分布反映了它们在被动拉伸和主动收缩之间相反的运动单位（MU）募集模式。这项 HD-sEMG 研究为被动拉伸和主动收缩之间痉挛性 BB 活动的空间关系提供了新的神经生理学证据，加深了我们对痉挛机制的认识。
ChiCTR2000032245。
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