双炔基和三炔基-2-三氟甲基喹啉的合成及光学性质

Synthesis and optical properties of bis- and tris-alkynyl-2-trifluoromethylquinolines.

作者信息

Jopp Stefan, Spruner von Mertz Franziska, Ehlers Peter, Villinger Alexander, Langer Peter

机构信息

Universität Rostock, Institut für Chemie, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.

Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Str. 29a, 18059 Rostock, Germany.

出版信息

Beilstein J Org Chem. 2024 May 29;20:1246-1255. doi: 10.3762/bjoc.20.107. eCollection 2024.

DOI:10.3762/bjoc.20.107

PMID:38887576

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11181212/

Abstract

Three bis- or tris-brominated 2-trifluoromethylquinolines have been successfully applied in palladium-catalysed Sonogashira reactions, leading to several examples of alkynylated quinolines in good to excellent yields. Optical properties of selected products have been studied by steady state absorption and fluorescence spectroscopy which give insights of the influence of the substitution pattern and of the type of substituents on the optical properties.

摘要

三种双溴或三溴代2-三氟甲基喹啉已成功应用于钯催化的Sonogashira反应，得到了几个炔基化喹啉的实例，产率良好至优异。通过稳态吸收和荧光光谱对选定产物的光学性质进行了研究，这有助于深入了解取代模式和取代基类型对光学性质的影响。