Makarov I V, Pushkin S Yu, Dmitrieva M A
Samara State Medical University, Samara, Russia.
Clinical Hospital RZD-Medicine, Samara, Russia.
Khirurgiia (Mosk). 2024(6):81-87. doi: 10.17116/hirurgia202406181.
We present successful surgical treatment of a patient with chronic kidney disease (CKD) and hyperparathyroidism undergoing renal replacement therapy. At baseline, parathyroidectomy via cervical access was performed for parathyroid adenomas. After 6 years, clinical and laboratory relapse of disease required thoracoscopic resection of atypically located anterior mediastinal adenoma. This case demonstrates that this disease is one of the most difficult in modern medicine requiring a special approach in diagnosis and treatment. Patients with CKD and hyperparathyroidism need for follow-up, control of total and ionized serum calcium, inorganic phosphorus and parathormone, osteodensitometry, ultrasound and scintigraphy of thyroid and parathyroid glands, and, if necessary, CT or MRI of the neck and chest organs.
我们展示了对一名接受肾脏替代治疗的慢性肾脏病(CKD)和甲状旁腺功能亢进患者的成功手术治疗。基线时,通过颈部入路对甲状旁腺腺瘤进行了甲状旁腺切除术。6年后,疾病的临床和实验室复发需要对非典型定位的前纵隔腺瘤进行胸腔镜切除。该病例表明,这种疾病是现代医学中最难治疗的疾病之一,需要特殊的诊断和治疗方法。CKD和甲状旁腺功能亢进患者需要进行随访,监测血清总钙、离子钙、无机磷和甲状旁腺激素,进行骨密度测定、甲状腺和甲状旁腺的超声及闪烁扫描,必要时还需对颈部和胸部器官进行CT或MRI检查。