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Long-Term Clinical and Radiographic Outcomes of Meniscus Allograft Transplant.半月板同种异体移植的长期临床和影像学结果
Curr Rev Musculoskelet Med. 2024 Sep;17(9):343-352. doi: 10.1007/s12178-024-09904-z. Epub 2024 Jun 18.
2
Minimum 10-Year Clinical Outcomes and Survivorship of Meniscal Allograft Transplantation With Fresh-Frozen Allografts Using the Bridge-in-Slot Technique.采用桥接式技术的新鲜冷冻同种异体移植物半月板移植的最低 10 年临床结果和存活率。
Am J Sports Med. 2023 Sep;51(11):2954-2963. doi: 10.1177/03635465231188657. Epub 2023 Aug 18.
3
Survivorship of 157 Arthroscopic Meniscal Allograft Transplants Using Bone Fixation at a Mean of 7 Years and Prognostic Factors Analysis.157 例采用骨固定技术的关节镜半月板同种异体移植术后 7 年的存活率及预后因素分析。
Am J Sports Med. 2024 Jan;52(1):96-108. doi: 10.1177/03635465231212667.
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Patients with advanced lateral osteoarthritis can return to sports and work after distraction arthroplasty plus lateral meniscal allograft transplantation combined with cartilage repair.晚期外侧骨关节炎患者在接受关节牵张成形术加外侧半月板同种异体移植联合软骨修复后可以重返运动和工作。
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The results of meniscal allograft transplantation surgery: what is success?半月板同种异体移植手术的结果:何为成功?
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Return to Sport and Patient Satisfaction After Meniscal Allograft Transplantation.半月板同种异体移植术后重返运动和患者满意度。
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引用本文的文献

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Centralization reduces meniscal extrusion, improves joint mechanics and functional outcomes in patients undergoing meniscus surgery: A systematic review and meta-analysis.集中化减少半月板挤出,改善半月板手术患者的关节力学和功能结果:一项系统评价和荟萃分析。
Knee Surg Sports Traumatol Arthrosc. 2025 Mar;33(3):888-906. doi: 10.1002/ksa.12410. Epub 2024 Aug 9.

本文引用的文献

1
Outcomes and Return to Sport After Knee Osteochondral Allograft Transplant in Professional Athletes.职业运动员膝关节异体骨软骨移植后的结果及恢复运动情况
Orthop J Sports Med. 2024 Feb 26;12(2):23259671241226738. doi: 10.1177/23259671241226738. eCollection 2024 Feb.
2
Survivorship of 157 Arthroscopic Meniscal Allograft Transplants Using Bone Fixation at a Mean of 7 Years and Prognostic Factors Analysis.157 例采用骨固定技术的关节镜半月板同种异体移植术后 7 年的存活率及预后因素分析。
Am J Sports Med. 2024 Jan;52(1):96-108. doi: 10.1177/03635465231212667.
3
Concomitant Treatment of High-Grade Cartilage Lesions Mitigates Risk of Meniscal Allograft Transplant Failure.同时治疗高级别软骨病变可降低半月板同种异体移植失败的风险。
Arthroscopy. 2024 May;40(5):1703-1713.e2. doi: 10.1016/j.arthro.2023.11.011. Epub 2023 Nov 25.
4
Minimum 10-Year Clinical Outcomes and Survivorship of Meniscal Allograft Transplantation With Fresh-Frozen Allografts Using the Bridge-in-Slot Technique.采用桥接式技术的新鲜冷冻同种异体移植物半月板移植的最低 10 年临床结果和存活率。
Am J Sports Med. 2023 Sep;51(11):2954-2963. doi: 10.1177/03635465231188657. Epub 2023 Aug 18.
5
Revision and Primary Meniscal Allograft Transplantations Provide Clinical Benefit at Mid-Term Follow-Up: A Matched-Cohort Analysis of Patient-Reported Outcomes, Reoperations, and Failures.翻修和初次半月板同种异体移植在中期随访时提供临床获益:患者报告的结果、再次手术和失败的匹配队列分析。
Arthroscopy. 2024 Feb;40(2):412-421.e1. doi: 10.1016/j.arthro.2023.06.047. Epub 2023 Jul 6.
6
Meniscal allograft transplantation, anterior cruciate ligament reconstruction, and valgus high tibial osteotomy for meniscal-deficient, unstable, and varus knees: surgical technique and clinical outcomes.半月板同种异体移植、前交叉韧带重建和内侧半月板缺失、不稳定和内翻膝的胫骨高位截骨术:手术技术和临床结果。
Int Orthop. 2023 Oct;47(10):2523-2535. doi: 10.1007/s00264-023-05846-2. Epub 2023 Jun 15.
7
Patient-Specific Variables Associated with Failure to Achieve Clinically Significant Outcomes After Meniscal Allograft Transplantation at Minimum 5 Year Follow-Up.在至少5年随访期内,与半月板同种异体移植术后未实现具有临床意义的结果相关的患者特异性变量。
Arthroscopy. 2023 Nov;39(11):2327-2338. doi: 10.1016/j.arthro.2023.03.031. Epub 2023 Apr 26.
8
Systematic Review of Clinical Results After Medial Meniscus Allograft Transplantation Reveals Improved Patient Reported Outcomes at Greater Than 5 Years Follow-Up.内侧半月板同种异体移植后临床结果的系统评价显示,超过 5 年随访时患者报告的结果得到改善。
Arthroscopy. 2023 Mar;39(3):802-811. doi: 10.1016/j.arthro.2022.11.033. Epub 2022 Dec 8.
9
Survivorship and Reoperation of 324 Consecutive Isolated or Combined Arthroscopic Meniscal Allograft Transplants Using Soft Tissue Fixation.324 例连续采用软组织固定的单纯或联合关节镜半月板同种异体移植的生存和再手术情况。
Am J Sports Med. 2023 Jan;51(1):119-128. doi: 10.1177/03635465221131522. Epub 2022 Nov 9.
10
Time to Achieving Clinically Significant Outcomes After Meniscal Allograft Transplantation.半月板移植术后达到临床显著结果的时间。
Cartilage. 2022 Jul-Sep;13(3):19476035221102568. doi: 10.1177/19476035221102568.

半月板同种异体移植的长期临床和影像学结果

Long-Term Clinical and Radiographic Outcomes of Meniscus Allograft Transplant.

作者信息

Phillips Andrew R, Haneberg Erik C, Boden Stephanie A, Yanke Adam B, Cole Brian J

机构信息

, Chicago, USA.

出版信息

Curr Rev Musculoskelet Med. 2024 Sep;17(9):343-352. doi: 10.1007/s12178-024-09904-z. Epub 2024 Jun 18.

DOI:10.1007/s12178-024-09904-z
PMID:38890265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11335704/
Abstract

PURPOSE OF REVIEW

To reduce pain, improve function and possibly mitigate the risk for development of osteoarthritis in patients with functionally deficient meniscus pathology, meniscal allograft transplantation (MAT) can be used to restore native joint biomechanics and increase knee joint longevity. This review explores the senior author's preferred bridge-in-slot technique and recently published long-term clinical and radiographic outcomes following MAT.

RECENT FINDINGS

Recent literature demonstrates MAT to be a safe and largely successful procedure for patients with functional meniscus deficiency. A majority of patients reach established minimal clinically important difference (MCID) values. Graft survivorship is approximately 80% at 10 years, significantly delaying and in some cases, preventing the need for future joint reconstruction procedures in these young patients. Return to sport rates are over 70%, revealing meniscal allografts can withstand high impact activities. Cartilage damage at the time of MAT increases the risk for graft and clinical failure, though this may be mitigated with a concomitant cartilage restoration procedure. Meniscal allograft transplantation can provide a durable and effective long-term solution to meniscal deficiency in symptomatic patients who wish to decrease the risk of symptomatic progression and possibly further osteoarthritis and continue activities of daily life and sports with less pain and more function. By restoring more normal joint biomechanics, MAT can mitigate the potential need for future knee arthroplasty in this young active patient population.

摘要

综述目的

为减轻功能不全的半月板病变患者的疼痛、改善功能并可能降低骨关节炎的发病风险,半月板同种异体移植(MAT)可用于恢复天然关节生物力学并延长膝关节寿命。本综述探讨了资深作者所青睐的槽内桥接技术以及MAT术后近期发表的长期临床和影像学结果。

最新发现

近期文献表明,MAT对于功能性半月板缺损患者而言是一种安全且基本成功的手术。大多数患者达到已确定的最小临床重要差异(MCID)值。移植物10年生存率约为80%,显著延迟且在某些情况下可避免这些年轻患者未来进行关节重建手术。恢复运动率超过70%,表明半月板同种异体移植物能够承受高强度活动。MAT时的软骨损伤会增加移植物和临床失败的风险,不过可通过同时进行软骨修复手术来减轻这种风险。半月板同种异体移植可为有症状的患者提供持久有效的长期半月板缺损解决方案,这些患者希望降低症状进展以及可能进一步发生骨关节炎的风险,并能在疼痛减轻且功能增强的情况下继续进行日常生活和运动。通过恢复更正常的关节生物力学,MAT可减少这一年轻活跃患者群体未来进行膝关节置换术的潜在需求。