Cozgarea Andreea, Cozma Dragoș, Teodoru Minodora, Lazăr-Höcher Alexandra-Iulia, Cirin Liviu, Faur-Grigori Adelina-Andreea, Lazăr Mihai-Andrei, Crișan Simina, Gaiță Dan, Luca Constantin-Tudor, Văcărescu Cristina
Institute of Cardiovascular Diseases Timisoara, 300310 Timisoara, Romania.
Department of Cardiology, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
J Clin Med. 2024 Jun 5;13(11):3328. doi: 10.3390/jcm13113328.
The rising prevalence of cardiovascular disease underscores the growing significance of heart failure (HF). Pathophysiological insights into HF highlight the dysregulation of the autonomic nervous system (ANS), characterized by sympathetic overactivity and diminished vagal tone, impacting cardiovascular function. Heart rate recovery (HRR), a metric measuring the heart's ability to return to its baseline rate post-exertion, plays a crucial role in assessing cardiovascular health. Widely applied across various cardiovascular conditions including HF, coronary artery disease (CAD), and arterial hypertension (HTN), HRR quantifies the difference between peak and recovery heart rates. Given its association with elevated sympathetic tone and exercise, HRR provides valuable insights into the perspective of HF, beyond effort tolerance, reaching toward prognostic and mortality indicators. Incorporating HRR into cardiovascular evaluations enhances our understanding of autonomic regulation in HF, offering potential implications for prognostication and patient management. This review addresses the significance of HRR in HF assessment, analyzing recently conducted studies, and providing a foundation for further research and clinical application.
心血管疾病患病率的上升凸显了心力衰竭(HF)日益增长的重要性。对HF的病理生理学认识强调了自主神经系统(ANS)的失调,其特征是交感神经活动过度和迷走神经张力降低,影响心血管功能。心率恢复(HRR)是衡量心脏在运动后恢复到基线心率能力的指标,在评估心血管健康方面起着至关重要的作用。HRR广泛应用于包括HF、冠状动脉疾病(CAD)和动脉高血压(HTN)在内的各种心血管疾病,它量化了峰值心率和恢复心率之间的差异。鉴于其与交感神经张力升高和运动的关联,HRR不仅能提供有关HF运动耐力的有价值见解,还能深入了解预后和死亡率指标。将HRR纳入心血管评估可增强我们对HF自主调节的理解,为预后评估和患者管理提供潜在意义。本综述阐述了HRR在HF评估中的重要性,分析了最近开展的研究,并为进一步研究和临床应用奠定了基础。