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局灶性癫痫持续状态及与血栓性血小板减少性紫癜相关的极端δ刷波

Focal Status Epilepticus and Extreme Delta Brush Associated With Thrombotic Thrombocytopenic Purpura.

作者信息

Yap Lauren E, Chen Huanwen, Ganji Sarah, Calabria Samuel E, Serrano Edwin J, Stemer Andrew B, Tirol Francis G, Jazebi Noushin

机构信息

Department of Neurology, MedStar Georgetown University Hospital, Washington, DC, USA.

National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

出版信息

Neurohospitalist. 2024 Jul;14(3):356-360. doi: 10.1177/19418744241245454. Epub 2024 Apr 1.

Abstract

Acute focal neurological deficits demand immediate evaluation. In this report, we present the case of a woman 20-some years of age with a history of hemolytic anemia and thrombocytopenia who presented with altered mental status and focal neurological deficits including aphasia, acute left gaze preference, right homonymous hemianopsia, right lower facial weakness, and right arm and leg weakness. Extensive neurological and hematological workup revealed that the patient suffered from focal status epilepticus associated with an extreme delta brush patten on electroencephalogram, likely secondary to thrombotic thrombocytopenic purpura. This case underscores the connection between hematological disorders and the neurological axis, emphasizing the critical role of integrating the neurological examination and neuroimaging findings to formulate an effective management plan.

摘要

急性局灶性神经功能缺损需要立即评估。在本报告中,我们介绍了一名20多岁的女性病例,她有溶血性贫血和血小板减少病史,出现了精神状态改变和局灶性神经功能缺损,包括失语、急性向左凝视偏好、右侧同向性偏盲、右侧面下部无力以及右侧手臂和腿部无力。广泛的神经学和血液学检查发现,该患者患有局灶性癫痫持续状态,脑电图显示有极端的δ刷状波模式,可能继发于血栓性血小板减少性紫癜。本病例强调了血液系统疾病与神经轴之间的联系,强调了整合神经学检查和神经影像学结果以制定有效管理计划的关键作用。

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本文引用的文献

1
Thrombotic thrombocytopenic purpura with neurological impairment: A Review.
Medicine (Baltimore). 2022 Dec 9;101(49):e31851. doi: 10.1097/MD.0000000000031851.
2
EEG-Delta brushes in DPPX encephalitis - Welcome to the club.
Clin Neurophysiol Pract. 2022 Dec 5;8:12-15. doi: 10.1016/j.cnp.2022.11.003. eCollection 2023.
3
Usefulness of arterial spin labeling in identifying status epilepticus secondary to acquired thrombotic thrombocytopenic purpura.
eNeurologicalSci. 2022 Nov 14;29:100435. doi: 10.1016/j.ensci.2022.100435. eCollection 2022 Dec.
4
Neurological manifestations of thrombotic microangiopathy syndromes in adult patients.
J Thromb Thrombolysis. 2021 May;51(4):1163-1169. doi: 10.1007/s11239-021-02431-5. Epub 2021 Mar 23.
5
Continuous EEG Findings in Autoimmune Encephalitis.
J Clin Neurophysiol. 2021 Mar 1;38(2):124-129. doi: 10.1097/WNP.0000000000000654.
6
Extreme delta brush and distinctive imaging in a pediatric patient with autoimmune GFAP astrocytopathy.
Mult Scler Relat Disord. 2018 Nov;26:121-123. doi: 10.1016/j.msard.2018.09.015. Epub 2018 Sep 13.
7
Immune-Thrombotic Thrombocytopenic Purpura is a Rare Cause of Ischemic Stroke in Young Adults: Case Reports and Literature Review.
J Stroke Cerebrovasc Dis. 2018 Nov;27(11):3163-3171. doi: 10.1016/j.jstrokecerebrovasdis.2018.07.017. Epub 2018 Sep 12.
8
Delta Brush Pattern Is Not Unique to NMDAR Encephalitis: Evaluation of Two Independent Long-Term EEG Cohorts.
Clin EEG Neurosci. 2018 Jul;49(4):278-284. doi: 10.1177/1550059417693168. Epub 2017 Feb 16.
9
Detection of anti-glutamic acid decarboxylase antibodies in immunoglobulin products.
J Allergy Clin Immunol Pract. 2018 Jan-Feb;6(1):260-261. doi: 10.1016/j.jaip.2017.04.042. Epub 2017 Jun 29.
10
Early ictal and interictal patterns in FIRES: The sparks before the blaze.
Epilepsia. 2017 Aug;58(8):1340-1348. doi: 10.1111/epi.13801. Epub 2017 May 26.

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