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2019 - 2023年采用高流量鼻导管给氧疗法治疗的犬芽生菌病病例系列:19例。

Case series of dogs with blastomycosis managed with high-flow nasal oxygen therapy (2019-2023): 19 cases.

作者信息

Tarosky Melanie, Haraschak Jenica L, Reinhart Jennifer M, Billhymer Audrey

机构信息

Department of Veterinary Clinical Medicine, University of Illinois Urbana-Champaign, Urbana, IL, United States.

出版信息

Front Vet Sci. 2024 Jun 5;11:1369259. doi: 10.3389/fvets.2024.1369259. eCollection 2024.

Abstract

OBJECTIVE

To describe the clinical presentation, progression, treatment, and outcome of dogs with blastomycosis treated with high-flow nasal oxygen therapy (HFNOT).

DESIGN

Retrospective case review.

SETTING

University veterinary teaching hospital.

ANIMALS

Nineteen client-owned dogs with strongly suspected or confirmed blastomycosis treated with HFNOT.

MEASUREMENTS AND MAIN RESULTS

The medical records of dogs with strongly suspected or confirmed blastomycosis between October 2019 and May 2023 that received HFNOT were evaluated. Nineteen dogs were included. Nine dogs were started directly on high-flow nasal oxygen therapy. The remaining 10 dogs first received traditional oxygen therapy and were then transitioned to HFNOT 3-142 h later. Of the 19 dogs, 1 survived to discharge from hospital, 12 were euthanized due to progression of disease, and 6 died during the hospitalization period.

CONCLUSIONS AND CLINICAL IMPORTANCE

The prognosis for survival of dogs with severe blastomycosis requiring therapy beyond traditional oxygen methods was poor to grave in this population. This is the first known documented report of HFNOT use in dogs with confirmed or suspected blastomycosis.

摘要

目的

描述接受高流量鼻导管给氧疗法(HFNOT)治疗的芽生菌病犬的临床表现、病情进展、治疗及预后情况。

设计

回顾性病例分析。

地点

大学兽医教学医院。

动物

19只由客户拥有的、高度怀疑或确诊为芽生菌病且接受HFNOT治疗的犬。

测量指标及主要结果

对2019年10月至2023年5月期间接受HFNOT治疗的高度怀疑或确诊为芽生菌病犬的病历进行评估。共纳入19只犬。9只犬直接开始接受高流量鼻导管给氧疗法。其余10只犬首先接受传统氧疗,然后在3 - 142小时后转为HFNOT治疗。19只犬中,1只存活出院,12只因病情进展实施安乐死,6只在住院期间死亡。

结论及临床意义

在这组病例中,需要传统氧疗以外治疗方法的重症芽生菌病犬的生存预后很差甚至极差。这是已知的首篇关于HFNOT用于确诊或疑似芽生菌病犬的文献报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf91/11188474/c839e38988a5/fvets-11-1369259-g001.jpg

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