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糖尿病足患者小足部截肢术后再截肢患病率:一项横断面研究

Reamputation prevalence after minor feet amputations in patients with diabetic foot, a cross sectional study.

作者信息

Sánchez Correa C A, Briceño Sanín I, Bautista Valencia J J, Niño M E, Robledo Quijano J

机构信息

Departamento de Ortopedia y Traumatología, Hospital Universitario de la Samaritana. Bogotá, Colombia.

Departamento de Ortopedia y Traumatología, Pontificia Universidad Javeriana, Hospital Universitario de San Ignacio, Bogotá, Colombia.

出版信息

Rev Esp Cir Ortop Traumatol. 2025 Jan-Feb;69(1):70-76. doi: 10.1016/j.recot.2024.06.009. Epub 2024 Jun 21.

Abstract

INTRODUCTION

Reported prevalence for reamputation in diabetic foot is diverse, risk factors are not clear for minor amputations. This study aims to determine the prevalence for reamputation in diabetic foot from minor amputations and to evaluate associated factors for such outcome.

METHODS

Cross sectional study developed in 2hospitals. Patients hospitalized for diabetic foot ulcer requiring a minor amputation were included. A descriptive analysis of all variables is presented, as well as prevalence ratios (PR) and a multivariate logistic regression.

RESULTS

The prevalence was of 48% for 15 years. Toes were the most frequent minor amputation that required reamputation and above the knee amputation was the most frequent reamputation level (45%). Variables whose PR was associated to reamputation risk were: smoking history (PR 1.32, CI 95%: 1.02-1.67, P=0.03), vascular occlusion in doppler (PR 1.47, CI 95%: 1.11-1.73, P=0.01), revascularization (PR 1.73, CI 95%: 1.31-2.14, P=0.00002), Wagner> 3 (PR 1.75, CI 95%: 1.16-1.84, P=0.01) and leucocytosis> 11,000 (PR 1.39, CI 95%: 1.07-1.68, P=0.01). Leucocytosis> 11,000, Wagner> 3, vascular occlusion in doppler and revascularization were the variables that best predicted the outcome. Furthermore, leucocytosis was the best variable for predicting reamputation (OR 2.4, CI 95%: 1.1-5.6, P=0.04).

CONCLUSIONS

Reamputation prevalence was 48%. The toes were the minor amputation more frequently requiring reamputation and above the knee was the most frequent reamputation level. Risk for reamputation was associated with variables related to vascular compromise and infection.

摘要

引言

糖尿病足再次截肢的报道患病率各不相同,小截肢的危险因素尚不清楚。本研究旨在确定糖尿病足小截肢后再次截肢的患病率,并评估导致该结果的相关因素。

方法

在两家医院开展横断面研究。纳入因糖尿病足溃疡住院且需要进行小截肢的患者。对所有变量进行描述性分析,并给出患病率比(PR)和多因素逻辑回归分析结果。

结果

15年的患病率为48%。脚趾是最常需要再次截肢的小截肢部位,而膝上截肢是最常见的再次截肢水平(45%)。PR与再次截肢风险相关的变量有:吸烟史(PR 1.32,95%置信区间:1.02 - 1.67,P = 0.03)、多普勒血管闭塞(PR 1.47,95%置信区间:1.11 - 1.73,P = 0.01)、血管重建(PR 1.73,95%置信区间:1.31 - 2.14,P = 0.00002)、瓦格纳分级>3(PR 1.75,95%置信区间:1.16 - 1.84,P = 0.01)和白细胞增多>11,000(PR 1.39,95%置信区间:1.07 - 1.68,P = 0.01)。白细胞增多>11,000、瓦格纳分级>3、多普勒血管闭塞和血管重建是最能预测该结果的变量。此外,白细胞增多是预测再次截肢的最佳变量(比值比2.4,95%置信区间:1.1 - 5.6,P = 0.04)。

结论

再次截肢患病率为48%。脚趾是最常需要再次截肢的小截肢部位,膝上截肢是最常见的再次截肢水平。再次截肢风险与血管受损和感染相关的变量有关。

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