Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Population Health Sciences, Weill Cornell Medical College, New York, NY.
Ann Vasc Surg. 2024 Dec;109:494-507. doi: 10.1016/j.avsg.2024.05.007. Epub 2024 Jun 26.
Investigate readmission rates, diagnoses associated with readmission, and associations with mortality through 90 days postoperatively after elective endovascular thoracic and thoracoabdominal aortic repair overall and by extent of coverage.
A cohort of index elective nontraumatic endovascular thoracic and thoracoabdominal aortic cases from 2010 to 2018 was derived from the Vascular Implant Surveillance and Interventional Outcomes Network. Cohort readmissions within 90 days postoperative were examined both overall and by Crawford extent (CE) of aortic coverage. Postoperative mortality was examined by reason for readmission and CE.
The cohort consisted of 2,105 patients who underwent endovascular thoracic and thoracoabdominal aortic repair (1,550 CE 0A/0B; 242 CE 1-3; 313 CE 4-5). Cumulative risk for 90-day readmission was 34.3% in CE 0A/0B repairs, 33.4% in CE 4-5 repairs, and 47.4% in CE 1-3 repairs. Compared with CE 0A/B, patients with CE 1-3 repairs experienced an increased risk of readmission within 90 days postoperatively after adjusting for preoperative factors (adjusted hazard ratio [HR] 1.27 [1.00, 1.61]), while the readmission risk for CE 4-5 repairs did not differ significantly (adjusted HR 0.83 [0.64, 1.06]). Significant risk factors for 90-day readmission included chronic obstructive pulmonary disease, dialysis dependence, limited ambulation, visceral/spinal ischemia, and in-hospital stroke. Discharge to home was protective against readmission (HR 0.65, confidence interval 0.54-0.79). Patients with a readmission within 90 days had a 7.89-fold increase in 90-day mortality (HR 7.84; 5.17, 11.9) compared with those not readmitted.
Increasing extent of endovascular thoracic and thoracoabdominal aortic repair was associated with higher 90-day readmission rates. Readmission for all CE was associated with near 8-fold increased risk of mortality. Risk factors associated with increased risk for readmission included pulmonary insufficiency, renal disease, and poor functional status. These findings can inform stakeholders about investment of resources to improve processes of care that both target prevention and mitigate risk of readmission after elective endovascular thoracic and thoracoabdominal aortic repair.
通过调查择期血管内胸主动脉和胸腹主动脉修复术后 90 天内的再入院率、再入院相关诊断以及与死亡率之间的关系,全面评估和按覆盖范围评估。
从 2010 年至 2018 年的血管植入物监测和介入结果网络中,得出了一组索引择期非外伤性血管内胸主动脉和胸腹主动脉病例队列。术后 90 天内的住院率,通过 Crawford 范围(CE)的主动脉覆盖范围进行全面和分类评估。通过再入院原因和 CE 评估术后死亡率。
该队列包括 2105 例接受血管内胸主动脉和胸腹主动脉修复的患者(CE0A/0B 为 1550 例;CE1-3 为 242 例;CE4-5 为 313 例)。CE0A/0B 修复术后 90 天内累积再入院风险为 34.3%,CE4-5 修复术后为 33.4%,CE1-3 修复术后为 47.4%。与 CE0A/B 相比,调整术前因素后,CE1-3 修复术患者术后 90 天内再入院的风险增加(调整后的危险比[HR]1.27[1.00,1.61]),而 CE4-5 修复术的再入院风险差异无统计学意义(调整后的 HR 0.83[0.64,1.06])。90 天再入院的显著危险因素包括慢性阻塞性肺疾病、透析依赖、活动能力有限、内脏/脊髓缺血和院内中风。出院回家可降低再入院风险(HR 0.65,置信区间 0.54-0.79)。与未再入院的患者相比,90 天内再入院的患者 90 天死亡率增加 7.89 倍(HR 7.84;5.17,11.9)。
血管内胸主动脉和胸腹主动脉修复范围的增加与 90 天内再入院率的增加有关。所有 CE 的再入院与近 8 倍的死亡率增加有关。与再入院风险增加相关的危险因素包括肺功能不全、肾脏疾病和功能状态不佳。这些发现可以为利益相关者提供信息,以投资资源改善择期血管内胸主动脉和胸腹主动脉修复后的护理流程,既可以针对预防,也可以减轻再入院的风险。