Siu Albert L, Leff Bruce
Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Geriatrics Research, Education, and Clinical Center (GRECC) at the James J. Peters VA Medical Center, Bronx, New York, USA.
J Am Geriatr Soc. 2024 Dec;72(12):3647-3655. doi: 10.1111/jgs.19042. Epub 2024 Jun 29.
For aging-related research, there is a pressing need to attend to the dissemination and implementation of evidence-based interventions. Some aging-related interventions with established effectiveness may be poorly disseminated and implemented due to behavioral, organizational, payment, or other constraints. To provide insight into the beginning to end process of translation and implementation, we present a case history of the three-decade progression of Hospital at Home (HaH) now nearing national dissemination. We summarize research at various phases with particular attention to implementation considerations. Reviewing over three decades of HaH-related research dating from initial discovery to translation and implementation, we found that the content and importance of different constructs (e.g., inner practice vs. outer environmental setting) and the choice of implementation strategies differed depending on implementation context (testing of effectiveness, scaling, or sustainability). Early effectiveness studies mostly examined implementation issues related to the intervention, the practice setting, and the individuals involved. However, explicit and early consideration of scale and sustainment was not the primary focus. For example, HaH program intake is primarily through hospital emergency departments (ED). Initial efforts would have benefited from incorporating strategies (e.g., incorporating ED leadership into program leadership) to address night and weekend admissions. Many regulatory barriers did not surface during initial considerations. Considering implementation issues late may contribute to delay in bringing discoveries to population impact. The experience with HaH suggests that scale and sustainability bear earlier consideration because barriers and facilitators to implementation are likely to be different in content and importance at different phases of implementation.
对于与衰老相关的研究,迫切需要关注基于证据的干预措施的传播和实施。一些已证实有效的与衰老相关的干预措施,可能由于行为、组织、支付或其他限制因素而传播和实施不佳。为了深入了解从翻译到实施的全过程,我们介绍了“居家医院”(HaH)三十年发展历程的案例,该模式目前正接近全国推广阶段。我们总结了各个阶段的研究,特别关注实施方面的考虑因素。回顾了从最初发现到翻译和实施的三十多年来与HaH相关的研究,我们发现不同构建要素(例如内部实践与外部环境)的内容和重要性以及实施策略的选择因实施背景(有效性测试、扩大规模或可持续性)而异。早期的有效性研究大多考察了与干预措施、实践环境和相关个体有关的实施问题。然而,对规模和可持续性的明确且早期的考虑并非主要重点。例如,HaH项目主要通过医院急诊科(ED)接收患者。最初的努力若能纳入一些策略(例如将急诊科领导纳入项目领导)以解决夜间和周末入院问题,本可从中受益。许多监管障碍在最初考虑时并未显现。后期才考虑实施问题可能会导致研究成果对人群产生影响的时间延迟。HaH的经验表明,规模和可持续性应更早得到考虑,因为在实施的不同阶段,实施的障碍和促进因素在内容和重要性上可能会有所不同。