Lo Joshua, Taweesedt Pahnwat T, Kawai Makoto
Department of Internal Medicine, Santa Clara Valley Medical Center, San Jose, CA 95128, United States.
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, United States.
World J Clin Oncol. 2024 Jun 24;15(6):677-683. doi: 10.5306/wjco.v15.i6.677.
Sleep problems have become a significant public health concern, affecting a large portion of the global population and have been linked to increased morbidity and mortality. The incidence of gastrointestinal (GI) cancers continues to rise, posing a substantial burden on healthcare systems worldwide. This editorial aims to delve into the impact of sleep on GI cancers, including esophageal, gastric, colorectal, hepatobiliary, and pancreatic cancer. Recent literature investigating the potential connections between GI cancers and sleep was reviewed. We considered aspects such as sleep duration, sleep disorders, and circadian rhythmicity, in order to explore the underlying mechanisms that can contribute to the development of GI cancers and propose avenues for future research.
睡眠问题已成为一个重大的公共卫生问题,影响着全球很大一部分人口,并与发病率和死亡率的增加有关。胃肠道(GI)癌症的发病率持续上升,给全球医疗系统带来了巨大负担。这篇社论旨在深入探讨睡眠对胃肠道癌症的影响,包括食管癌、胃癌、结直肠癌、肝胆癌和胰腺癌。回顾了最近研究胃肠道癌症与睡眠之间潜在联系的文献。我们考虑了睡眠时间、睡眠障碍和昼夜节律等方面,以探索可能导致胃肠道癌症发生的潜在机制,并提出未来研究的方向。