Akhil Nayakawadi, Taksande Amar, Meshram Revat J, Wandile Shailesh, Javvaji Chaitanya Kumar
Paediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 May 30;16(5):e61401. doi: 10.7759/cureus.61401. eCollection 2024 May.
Infective endocarditis (IE) is a severe infection of the endocardium, frequently involving heart valves, and is associated with significant morbidity and mortality. At the same time, traditional complications of IE, such as valvular dysfunction and embolic events, are well-documented, and uncommon cardiac manifestations, such as chorda tendinea rupture and pulmonary valve vegetation, present unique diagnostic and management challenges. This comprehensive review explores the pathophysiology, clinical presentation, diagnostic strategies, and management approaches for IE's chorda tendinea rupture and pulmonary valve vegetation. Through a detailed examination of the literature and discussion of clinical scenarios, we highlight the importance of recognizing these rare complications and discuss the implications for clinical practice. Additionally, we identify knowledge gaps and propose areas for future research to enhance further our understanding and management of these unusual cardiac complications in IE. This review aims to provide clinicians with valuable insights to improve patient care and outcomes in the challenging setting of infective endocarditis.
感染性心内膜炎(IE)是一种严重的心内膜感染,常累及心脏瓣膜,且与显著的发病率和死亡率相关。同时,IE的传统并发症,如瓣膜功能障碍和栓塞事件,已有充分记录,而罕见的心脏表现,如腱索断裂和肺动脉瓣赘生物,则带来了独特的诊断和管理挑战。这篇综述探讨了IE腱索断裂和肺动脉瓣赘生物的病理生理学、临床表现、诊断策略及管理方法。通过对文献的详细审视和临床病例讨论,我们强调了识别这些罕见并发症的重要性,并讨论其对临床实践的意义。此外,我们明确了知识空白,并提出未来研究方向,以进一步加深我们对IE中这些不寻常心脏并发症的理解和管理。本综述旨在为临床医生提供有价值的见解,以改善感染性心内膜炎这一具有挑战性环境下的患者护理及治疗效果。