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萘丸摄入导致血管内溶血和急性肾损伤。

Naphthalene Ball Ingestion Leading to Intravascular Hemolysis and Acute Kidney Injury.

作者信息

Sravanthi Kasireddy, Patil Manojkumar G, Mane Shailaja, Garlapati Srinija

机构信息

Pediatrics, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune (Deemed to be University), Pune, IND.

出版信息

Cureus. 2024 May 29;16(5):e61291. doi: 10.7759/cureus.61291. eCollection 2024 May.

DOI:10.7759/cureus.61291
PMID:38947700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11212845/
Abstract

Naphthalene is an aromatic hydrocarbon found in mothballs, deodorizers, or insecticides. Naphthalene poisoning is not commonly seen in the pediatric age group due to its pungent odor and taste, water insolubility, and poor absorption from the gastrointestinal tract (GIT). This case report describes a five-year-old boy who experienced accidental naphthalene mothball ingestion resulting in intravascular hemolysis and acute kidney injury (AKI). Naphthalene exposure can cause severe complications, especially in children. The clinical presentation included fever, abdominal pain, vomiting, decreased urine output, and hematuria. The laboratory findings revealed hemolytic anemia, elevated serum creatinine, and proteinuria. The child received supportive treatment including intravenous fluids, packed red blood cell transfusions, and hemodialysis for AKI. Early diagnosis and intervention are crucial for a favorable outcome. This case highlights the importance of considering naphthalene poisoning in the differential diagnosis of children with hemolysis and AKI.

摘要

萘是一种芳香烃,存在于樟脑丸、除臭剂或杀虫剂中。由于其刺鼻的气味和味道、不溶于水以及在胃肠道(GIT)中吸收不良,萘中毒在儿童年龄组中并不常见。本病例报告描述了一名五岁男孩,他意外摄入萘樟脑丸,导致血管内溶血和急性肾损伤(AKI)。萘暴露可引起严重并发症,尤其是在儿童中。临床表现包括发热、腹痛、呕吐、尿量减少和血尿。实验室检查结果显示溶血性贫血、血清肌酐升高和蛋白尿。该患儿接受了包括静脉输液、浓缩红细胞输血以及针对急性肾损伤的血液透析在内的支持治疗。早期诊断和干预对于取得良好预后至关重要。本病例强调了在对溶血和急性肾损伤患儿进行鉴别诊断时考虑萘中毒的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83c2/11212845/06179578e686/cureus-0016-00000061291-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83c2/11212845/06179578e686/cureus-0016-00000061291-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83c2/11212845/06179578e686/cureus-0016-00000061291-i01.jpg