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回顾性评估射频容积组织减容术治疗短头型气道阻塞综合征犬鼻甲肥大。

Retrospective evaluation of radiofrequency volumetric tissue reduction for hypertrophic turbinates in dogs with brachycephalic obstructive airway syndrome.

机构信息

HNO-Chirurgie von Doernberg, Alzey, Germany.

Center for Applied Biotechnology and Molecular Medicine (CABMM), University of Zurich, Zurich, Switzerland.

出版信息

PLoS One. 2024 Jul 1;19(7):e0306391. doi: 10.1371/journal.pone.0306391. eCollection 2024.

Abstract

OBJECTIVE

The objective of this study was to retrospectively assess the effect of Radiofrequency Volumetric Tissue Reduction (RFVTR) on hypertrophic turbinates and clinical outcome in brachycephalic dogs when included in multi-level surgery (MLS).

STUDY DESIGN

Clinical retrospective multicenter study.

ANIMALS

132 client-owned brachycephalic dogs.

METHODS

132 brachycephalic dogs with high-grade Brachycephalic Obstructive Airway Ayndrome (BOAS) and hypertrophic turbinates were treated with RFVTR as part of MLS of the upper airways. Intranasal obstruction was evaluated by computer tomography (CT) and antero-/retrograde rhinoscopy before and 6 months after RFVTR. The clinical records, the CT images and the rhinoscopy videos were reviewed and clinical evolution was evaluated using a standardized questionnaire. The data was scored semi-quantitatively.

RESULTS

In this study, 132 patients were included for a follow-up period of 120 weeks. RFVTR resulted in minor complications, including serous nasal discharge within the first postoperative week in all dogs, and intermittent nasal congestion between 3-8 weeks after treatment in 24.3% of the patients. Rhinoscopy and CT follow-ups were available for 33 patients. Six months after treatment intranasal airspace was increased (p = 0.002) and the presence and overall amount of mucosal contact points was reduced (p = 0.039).

CONCLUSION

MLS with RFVTR led to a significant reduction in turbinate volume at the 6-month follow-up examination and significant clinical improvement over a long-term period of 120 weeks. This suggests the viability of RFVTR as a turbinate-preserving treatment for intranasal obstruction in dogs with BOAS.

CLINICAL SIGNIFICANCE

RFVTR is a minimally invasive turbinoplasty technique for intranasal obstruction in dogs with BOAS and can be included in MLS without increasing complication rates.

摘要

目的

本研究旨在回顾性评估射频鼻甲容积减少术(RFVTR)在多层面手术(MLS)中治疗短头畸形犬鼻甲肥大和临床效果。

研究设计

临床回顾性多中心研究。

动物

132 只患有重度短头型气道阻塞综合征(BOAS)和鼻甲肥大的患犬。

方法

132 只短头型犬因重度 BOAS 和鼻甲肥大接受 RFVTR 治疗,作为上呼吸道 MLS 的一部分。术前和术后 6 个月通过计算机断层扫描(CT)和鼻前/后镜评估鼻腔阻塞。回顾临床记录、CT 图像和鼻镜视频,并使用标准化问卷评估临床演变。数据进行半定量评分。

结果

本研究共纳入 132 例患者,随访时间为 120 周。RFVTR 导致轻微并发症,所有犬术后第一周均出现浆液性鼻腔分泌物,24.3%的犬在治疗后 3-8 周出现间歇性鼻塞。33 例患者进行了鼻镜和 CT 随访。治疗后 6 个月,鼻腔内空气空间增加(p = 0.002),黏膜接触点的存在和总体数量减少(p = 0.039)。

结论

RFVTR 联合 MLS 可显著减少鼻甲体积,且在 120 周的长期随访中,临床症状显著改善。这表明 RFVTR 作为一种保留鼻甲的治疗方法,可用于治疗 BOAS 犬的鼻腔阻塞。

临床意义

RFVTR 是一种治疗 BOAS 犬鼻腔阻塞的微创鼻甲成形术,可与 MLS 联合使用,且不会增加并发症发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96e/11216595/e3aaac99f20e/pone.0306391.g001.jpg

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