Dai Weilei, Zhong Ting, Chen Feng, Shen Miaomiao, Zhu Liya
Weilei Dai Department of Nursing, Jiaxing Hospital of Traditional Chinese Medicine Jiaxing, Zhejiang Province 314001, P.R. China.
Ting Zhong Department of ICU, Jiaxing Hospital of Traditional Chinese Medicine Jiaxing, Zhejiang Province 314001, P.R. China.
Pak J Med Sci. 2024 Jul;40(6):1129-1134. doi: 10.12669/pjms.40.6.9307.
To identify independent risk factors of pulmonary infection in intensive care unit (ICU) patients, and to construct a prediction model.
Medical data of 398 patients treated in the ICU of Jiaxing Hospital of Traditional Chinese Medicine from January 2019 to January 2023 were analyzed. Univariate and multivariate logistic regression analyses were used to identify independent risk factors for pulmonary infection in ICU patients. R software was used to construct a nomogram prediction model, and the prediction model was internally validated using computer simulation bootstrap method. Predictive value of the model was analyzed using the receiver operating characteristic (ROC) curve.
A total of 97 ICU patients (24.37%) developed pulmonary infection. Age, ICU stay time, invasive operation, diabetes, duration of mechanical ventilation, and state of consciousness were all identified as risk factors for pulmonary infection. The calibration curve of the constructed nomogram prediction model showed a good consistency between the predicted value of the model and the actual observed value. ROC curve analysis showed that the area under the curve (AUC) of the model was 0.784 (95% CI: 0.731-0.837), indicating a certain predictive value.
Age, length of stay in ICU, invasive operation, diabetes, duration of mechanical ventilation, and state of consciousness are risk factors for pulmonary infection in ICU patients. The nomogram prediction model constructed based on the above risk factors has shown a good predictive value.
识别重症监护病房(ICU)患者肺部感染的独立危险因素,并构建预测模型。
分析2019年1月至2023年1月在嘉兴市中医医院ICU接受治疗的398例患者的医疗数据。采用单因素和多因素logistic回归分析来识别ICU患者肺部感染的独立危险因素。使用R软件构建列线图预测模型,并采用计算机模拟自举法对预测模型进行内部验证。使用受试者工作特征(ROC)曲线分析模型的预测价值。
共有97例ICU患者(24.37%)发生肺部感染。年龄、ICU住院时间、侵入性操作、糖尿病、机械通气时间和意识状态均被确定为肺部感染的危险因素。构建的列线图预测模型的校准曲线显示模型预测值与实际观察值之间具有良好的一致性。ROC曲线分析显示模型的曲线下面积(AUC)为0.784(95%CI:0.731-0.837),表明具有一定的预测价值。
年龄、ICU住院时间、侵入性操作、糖尿病、机械通气时间和意识状态是ICU患者肺部感染的危险因素。基于上述危险因素构建的列线图预测模型已显示出良好的预测价值。