Construction of a prediction model for pulmonary infection and its risk factors in Intensive Care Unit patients.

作者信息

Dai Weilei, Zhong Ting, Chen Feng, Shen Miaomiao, Zhu Liya

机构信息

Weilei Dai Department of Nursing, Jiaxing Hospital of Traditional Chinese Medicine Jiaxing, Zhejiang Province 314001, P.R. China.

Ting Zhong Department of ICU, Jiaxing Hospital of Traditional Chinese Medicine Jiaxing, Zhejiang Province 314001, P.R. China.

出版信息

Pak J Med Sci. 2024 Jul;40(6):1129-1134. doi: 10.12669/pjms.40.6.9307.

Abstract

OBJECTIVE

To identify independent risk factors of pulmonary infection in intensive care unit (ICU) patients, and to construct a prediction model.

METHODS

Medical data of 398 patients treated in the ICU of Jiaxing Hospital of Traditional Chinese Medicine from January 2019 to January 2023 were analyzed. Univariate and multivariate logistic regression analyses were used to identify independent risk factors for pulmonary infection in ICU patients. R software was used to construct a nomogram prediction model, and the prediction model was internally validated using computer simulation bootstrap method. Predictive value of the model was analyzed using the receiver operating characteristic (ROC) curve.

RESULTS

A total of 97 ICU patients (24.37%) developed pulmonary infection. Age, ICU stay time, invasive operation, diabetes, duration of mechanical ventilation, and state of consciousness were all identified as risk factors for pulmonary infection. The calibration curve of the constructed nomogram prediction model showed a good consistency between the predicted value of the model and the actual observed value. ROC curve analysis showed that the area under the curve (AUC) of the model was 0.784 (95% CI: 0.731-0.837), indicating a certain predictive value.

CONCLUSIONS

Age, length of stay in ICU, invasive operation, diabetes, duration of mechanical ventilation, and state of consciousness are risk factors for pulmonary infection in ICU patients. The nomogram prediction model constructed based on the above risk factors has shown a good predictive value.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3146/11190388/4d9a12fc05f0/PJMS-40-1129-g001.jpg

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