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成人糖尿病肾病患者血脂管理临床实践指南:英国临床糖尿病学家协会和英国肾脏病协会联合指南(ABCD-UKKA)2024 年版概要

Clinical practice guideline for the management of lipids in adults with diabetic kidney disease: abbreviated summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2024.

机构信息

East and North Herts NHS Trust, Hertfordshire, UK.

University of Glasgow, Glasgow, UK.

出版信息

BMC Nephrol. 2024 Jul 6;25(1):216. doi: 10.1186/s12882-024-03664-1.


DOI:10.1186/s12882-024-03664-1
PMID:38971750
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11227212/
Abstract

The contribution of chronic kidney disease (CKD) towards the risk of developing cardiovascular disease (CVD) is magnified with co-existing type 1 or type 2 diabetes. Lipids are a modifiable risk factor and good lipid management offers improved outcomes for people with diabetic kidney disease (DKD).The primary purpose of this guideline, written by the Association of British Clinical Diabetologists (ABCD) and UK Kidney Association (UKKA) working group, is to provide practical recommendations on lipid management for members of the multidisciplinary team involved in the care of adults with DKD.

摘要

慢性肾脏病(CKD)合并 1 型或 2 型糖尿病会显著增加心血管疾病(CVD)的发病风险。血脂是一个可改变的危险因素,良好的血脂管理可以改善糖尿病肾病(DKD)患者的预后。本指南由英国临床糖尿病学家协会(ABCD)和英国肾脏病协会(UKKA)工作组撰写,主要目的是为多学科团队成员提供有关 DKD 成人血脂管理的实用建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3315/11227212/0948e6483dd7/12882_2024_3664_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3315/11227212/0948e6483dd7/12882_2024_3664_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3315/11227212/0948e6483dd7/12882_2024_3664_Fig1_HTML.jpg

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[3]
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[4]
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Diabet Med. 2025-2

[5]
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本文引用的文献

[1]
Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients.

N Engl J Med. 2023-4-13

[2]
Inclisiran and cardiovascular events: a patient-level analysis of phase III trials.

Eur Heart J. 2023-1-7

[3]
Clinical practice guidelines for management of hyperglycaemia in adults with diabetic kidney disease.

Diabet Med. 2022-4

[4]
Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British Clinical Diabetologists and the Renal Association UK guideline update 2021.

BMC Nephrol. 2022-1-3

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Rationale and design of the CLEAR-outcomes trial: Evaluating the effect of bempedoic acid on cardiovascular events in patients with statin intolerance.

Am Heart J. 2021-5

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JAMA. 2020-12-8

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Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia.

N Engl J Med. 2020-4-16

[8]
Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol.

N Engl J Med. 2020-3-18

[9]
Effect of Bempedoic Acid vs Placebo Added to Maximally Tolerated Statins on Low-Density Lipoprotein Cholesterol in Patients at High Risk for Cardiovascular Disease: The CLEAR Wisdom Randomized Clinical Trial.

JAMA. 2019-11-12

[10]
Effects of Renal Impairment on the Pharmacokinetics, Efficacy, and Safety of Inclisiran: An Analysis of the ORION-7 and ORION-1 Studies.

Mayo Clin Proc. 2019-10-17

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