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糖尿病与非糖尿病患者尺神经卡压的术前处理。

Presurgical management of ulnar nerve entrapment in patients with and without diabetes mellitus.

机构信息

Department of Translational Medicine - Hand Surgery, Lund University, Malmö, Sweden.

Department of Hand Surgery, Skåne University Hospital, Malmö, Sweden.

出版信息

Sci Rep. 2024 Jul 6;14(1):15595. doi: 10.1038/s41598-024-66592-y.

Abstract

Diabetes mellitus (DM) is a risk factor for the development of ulnar nerve entrapment (UNE). Differences in surgical outcomes for UNE between patients with and without DM have been reported, but studies on presurgical management are scarce. This study aimed to evaluate the presurgical management of UNE in patients with (DM diagnosis < 2 years of UNE diagnosis) and without DM regarding the level of care for diagnosis and the proportion that proceeds to surgery. Data from 6600 patients with UNE between 2004 and 2019 were included from the Skåne Health Care Register (SHR) and cross-linked with data from the Swedish National Diabetes Register (NDR). The group with UNE and DM was compared to the group with UNE without DM and prevalence ratios were calculated using Cox regression analysis. Patients with DM more often got their first UNE diagnosis in secondary care than in primary care (643/667, 96% vs. 5361/5786; 93%). Patients with and without DM, regardless of the type of DM, presence of retinopathy, or HbA1c levels, were surgically treated for UNE to the same extent (258/667, 39% of patients with DM vs. 2131/5786, 37% of patients without DM). The proportion of surgically treated was significantly lower among patients diagnosed with UNE in primary care compared to secondary care (59/449, 13% vs. 2330/5786, 38%). Men were more often surgically treated than women (1228/3191, 38% vs.1161/3262 36%). Patients with UNE and DM are surgically treated to the same extent as patients with UNE but without DM and are more likely to be diagnosed in specialized care.

摘要

糖尿病(DM)是尺神经卡压(UNE)发生的危险因素。已有报道称,合并糖尿病和不合并糖尿病的患者的UNE 手术效果存在差异,但针对术前管理的研究较少。本研究旨在评估 2004 年至 2019 年间,在斯堪尼亚医疗保健登记处(SHR)中患有(DM 诊断时间距 UNE 诊断时间<2 年)和不患有 DM 的 UNE 患者的术前管理情况,包括对诊断的护理水平和进行手术的比例。将来自 SHR 的 6600 例 UNE 患者的数据与来自瑞典国家糖尿病登记处(NDR)的数据进行交叉链接。将 UNE 合并 DM 组与 UNE 不合并 DM 组进行比较,并使用 Cox 回归分析计算患病率比。与在初级保健中接受诊断相比,DM 患者更常在二级保健中首次被诊断出 UNE(643/667,96%比 5361/5786,93%)。无论 DM 类型、是否存在视网膜病变或 HbA1c 水平如何,患有和不患有 DM 的患者接受 UNE 手术治疗的比例相同(258/667,39%的 DM 患者比 2131/5786,37%的非 DM 患者)。在初级保健中诊断出 UNE 的患者中,手术治疗的比例明显低于在二级保健中诊断出 UNE 的患者(59/449,13%比 2330/5786,38%)。男性接受手术治疗的比例高于女性(1228/3191,38%比 1161/3262,36%)。患有 UNE 和 DM 的患者接受手术治疗的比例与患有 UNE 但不合并 DM 的患者相同,并且更可能在专科治疗中被诊断出。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9151/11227510/939bcbe40b0e/41598_2024_66592_Fig1_HTML.jpg

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