Department of Gynecology, Obstetrics and Women's Health, University of Missouri, Columbia, MO 65212, USA.
Department of Gynecology, Obstetrics and Women's Health, University of Missouri, Columbia, MO 65212, USA; Department of Gynecology and Obstetrics, Duke University, Durham, NC 27708, USA.
Eur J Obstet Gynecol Reprod Biol. 2024 Sep;300:29-34. doi: 10.1016/j.ejogrb.2024.06.046. Epub 2024 Jul 4.
Obstructive sleep apnea (OSA) is a frequent condition during pregnancy and its occurrence is increased in obese women. There are growing concerns about both pre-existing OSA and the development of gestational OSA and their effect on maternal pregnancy outcomes, fetal development, and even early childhood. A strong body of research has revealed maternal complications of OSA, but far fewer studies explore its impact on the developing fetus, highlighting an important area of future research. As evidence in both areas mounts about the negative reproductive impact of OSA, studies have emerged that explore the limitations of current diagnostic criteria and screening tools for this disorder in pregnancy which, in turn, limit the practitioner's ability to appropriately refer patients for OSA diagnosis and treatment. This expert review summarizes the current data regarding OSA screening tools in pregnancy, the limitations of these tools, and available OSA treatments and their efficacies. Our objective is to develop recommendations for how to best screen and manage OSA in pregnancy. We conclude that improved understanding of available tools and treatments will allow the obstetric practitioner to better counsel patients and help mitigate the deleterious effects of OSA on mother and fetus. We herein propose a clinical approach for the screening and management of OSA in pregnancy.
阻塞性睡眠呼吸暂停(OSA)是妊娠期间常见的病症,在肥胖女性中更为常见。人们越来越关注孕前 OSA 和妊娠期间 OSA 的发展,以及它们对孕产妇妊娠结局、胎儿发育,甚至儿童早期的影响。大量研究揭示了 OSA 的母体并发症,但很少有研究探讨其对发育中胎儿的影响,这凸显了未来研究的一个重要领域。随着关于 OSA 对生殖负面影响的证据越来越多,出现了一些研究探讨了目前妊娠期间该疾病诊断标准和筛查工具的局限性,这反过来又限制了从业者适当为 OSA 诊断和治疗转介患者的能力。本专家综述总结了目前关于妊娠期间 OSA 筛查工具的数据、这些工具的局限性,以及现有的 OSA 治疗方法及其疗效。我们的目标是制定如何在妊娠期间最好地筛查和管理 OSA 的建议。我们得出结论,更好地了解现有的工具和治疗方法将使产科医生能够更好地为患者提供咨询,并帮助减轻 OSA 对母亲和胎儿的有害影响。我们在此提出了一种用于妊娠期间 OSA 筛查和管理的临床方法。