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使用飞秒激光进行含基质植入的Bowman层移植:3年结果

Bowman Layer Transplantation With Stromal Inclusion Using Femtosecond Laser: 3-Year Results.

作者信息

Estrada-Mata Aranza Guadalupe, Benedetti Sandner Mónica, García de Oteyza Gonzalo, Gutiérrez-García Diana Karla, Nishimura-Crespo Areli, De la Torre González Carlos Enrique, De Wit Carter Guillermo, García-Albisua Ana Mercedes

机构信息

Asociación para Evitar la Ceguera en México, Hospital Luis Sánchez Bulnes, Universidad Nacional Autónoma de México, San Lucas, México; and.

Clínica Oftalmológica García de Oteyza, Barcelona, Spain.

出版信息

Cornea. 2025 Mar 1;44(3):332-336. doi: 10.1097/ICO.0000000000003620. Epub 2024 Jul 10.

Abstract

PURPOSE

The aim of this study was to evaluate the 3-year clinical results of Bowman layer with stromal inclusion (Bowman layer) transplantation using femtosecond laser for patients with advanced keratoconus.

METHODS

This single-center retrospective study included 7 eyes of 7 patients diagnosed with progressive keratoconus who underwent Bowman layer transplantation with stromal inclusion between 2018 and 2020. Follow-up was carried out from the date of surgery until 36 months later. Bowman layer grafts were positioned into a mid-stromal pocket performed by a femtosecond laser and patients were evaluated up to 3 years after surgery.

RESULTS

Corneal flattening of 5.49 D ( P = 0.0020) in Kmax was observed, increased in corneal pachymetry, and an improvement best-corrected visual acuity measured in logarithm of minimum angle of resolution (LogMAR) from 0.89 to 0.60 and tolerance to contact lens from 42% of the patients to 100% of them. Stabilization of the cornea was achieved in 100% with no further progression of the keratoconus; all surgical procedures were uneventful, and no complications were observed during the 3 years of follow-up.

CONCLUSIONS

Bowman layer transplantation with stromal inclusion flattened the cornea improving best-corrected visual acuity and contact lens tolerance and stabilized keratoconus in 100% of the patients during 3 years of follow-up and may be a feasible option in patients with advanced and progressive KC to delay or avoid the need for PK or DALK.

摘要

目的

本研究旨在评估飞秒激光辅助下带基质植入的Bowman层(Bowman层)移植术治疗晚期圆锥角膜患者的3年临床效果。

方法

本单中心回顾性研究纳入了2018年至2020年间7例诊断为进行性圆锥角膜的患者的7只眼,这些患者接受了带基质植入的Bowman层移植术。从手术日期开始随访至36个月后。将Bowman层移植物置于飞秒激光制作的基质中层口袋内,并对患者进行术后3年的评估。

结果

观察到最大角膜曲率(Kmax)角膜变平5.49 D(P = 0.0020),角膜厚度增加,最佳矫正视力以最小分辨角对数(LogMAR)衡量从0.89提高到0.60,佩戴隐形眼镜的耐受性从42%的患者提高到100%的患者。100%的患者角膜实现稳定,圆锥角膜无进一步进展;所有手术过程均顺利,在3年随访期间未观察到并发症。

结论

带基质植入的Bowman层移植术使角膜变平,提高了最佳矫正视力和隐形眼镜耐受性,并在3年随访期间使100%的患者圆锥角膜得到稳定,对于晚期进行性圆锥角膜患者可能是一种可行的选择,以延迟或避免穿透性角膜移植术(PK)或深板层角膜移植术(DALK)的需要。

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