Gupta Akarshi, Dixit Rashmi, Prakash Anjali
Department of Radiodiagnosis, Lok Nayak Hospital - Maulana Azad Medical College, New Delhi, India.
Radiol Bras. 2024 May 7;57:e20230125. doi: 10.1590/0100-3984.2023.0125. eCollection 2024 Jan-Dec.
To evaluate the diagnostic accuracy of multi-echo Dixon magnetic resonance imaging (MRI) in hepatic fat quantification, in comparison with that of magnetic resonance spectroscopy (MRS), on 3.0-T MRI.
Fifty-five adults with no known liver disease underwent MRI in a 3.0-T scanner for determination of the hepatic fat fraction, with two techniques: multi-echo Dixon, in a manually drawn region of interest (ROI) and in the entire liver parenchyma (automated segmentation); and MRS. The diagnostic accuracy and cutoff value for multi-echo Dixon were determined, with MRS being used as the reference standard.
The mean fat fraction obtained by multi-echo Dixon in the manually drawn ROI and in the entire liver was 5.2 ± 5.8% and 6.6 ± 5.2%, respectively, whereas the mean hepatic fat fraction obtained by MRS was 5.7 ± 6.4%. A very strong positive correlation and good agreement were observed between MRS and multi-echo Dixon, for the ROI (r = 0.988, r = 0.978, < 0.001) and for the entire liver parenchyma (r = 0.960, r = 0.922, < 0.001). A moderate positive correlation was observed between the hepatic fat fraction and body mass index of the participants, regardless of the fat estimation technique employed.
For hepatic fat quantification, multi-echo Dixon MRI demonstrated a very strong positive correlation and good agreement with MRS (often considered the gold-standard noninvasive technique). Because multi-echo Dixon MRI is more readily available than is MRS, it can be used as a rapid tool for hepatic fat quantification, especially when the hepatic fat distribution is not homogeneous.
在3.0-T磁共振成像（MRI）上，与磁共振波谱（MRS）相比，评估多回波狄克逊磁共振成像（MRI）在肝脏脂肪定量诊断中的准确性。
55名无已知肝脏疾病的成年人在3.0-T扫描仪上接受MRI检查，以通过两种技术测定肝脏脂肪分数：多回波狄克逊技术，在手动绘制的感兴趣区域（ROI）和整个肝实质（自动分割）中进行；以及MRS。以MRS作为参考标准，确定多回波狄克逊技术的诊断准确性和临界值。
多回波狄克逊技术在手动绘制的ROI和整个肝脏中获得的平均脂肪分数分别为5.2±5.8%和6.6±5.2%，而MRS获得的平均肝脏脂肪分数为5.7±6.4%。对于ROI（r = 0.988，r = 0.978，<0.001）和整个肝实质（r = 0.960，r = 0.922，<0.001），MRS与多回波狄克逊技术之间观察到非常强的正相关性和良好的一致性。无论采用何种脂肪估计技术，参与者的肝脏脂肪分数与体重指数之间均观察到中度正相关性。
对于肝脏脂肪定量，多回波狄克逊MRI与MRS（通常被认为是金标准非侵入性技术）显示出非常强的正相关性和良好的一致性。由于多回波狄克逊MRI比MRS更容易获得，它可以用作肝脏脂肪定量的快速工具，尤其是当肝脏脂肪分布不均匀时。
