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肥胖孕妇的围产期胎儿体重预测。

Peripartum Prediction of Fetal Weight in Gravidas With Obesity.

机构信息

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine and Ultrasound, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

出版信息

J Ultrasound Med. 2024 Oct;43(10):1903-1910. doi: 10.1002/jum.16523. Epub 2024 Jul 12.

Abstract

OBJECTIVES

Estimated fetal weight (EFW) is an important metric at delivery as neonates with abnormal birthweight and their mothers are at higher risk of birth complications. Data regarding optimal EFW assessment in gravidas with obesity is inconsistent, and with the increasing incidence of obesity, clarification of this question is crucial. We aimed to compare accuracy of ultrasound (US)-derived EFW and clinical assessments of EFW in predicting neonatal birthweight among gravidas with obesity.

METHODS

This prospective cohort study enrolled gravidas with obesity and a singleton pregnancy admitted for delivery at term. EFW was determined using either US biometry or clinical assessment (Leopold's maneuvers, Johnson's formula, and Insler's formula) at time of admission. Our primary outcome was accurate EFW, defined as EFW within 500 g of birthweight. Secondary outcomes included ability to predict small-for-gestational age (SGA) and large-for-gestational age (LGA) birthweights. These outcomes were compared between all EFW methods.

RESULTS

A total of 250 gravidas with a median body mass index of 36.4 kg/m were enrolled. Admission US outperformed Leopold's maneuvers in obtaining accurate EFW (81.6% versus 74.5%, P = .03). When comparing all methods, Johnson's and Insler's formulae performed the worst, accurately predicting EFW in only 27.4% and 14.3% of cases, respectively. Likewise, US-derived EFW outperformed Leopold's maneuvers and fundal height in the prediction of SGA and LGA neonates.

CONCLUSIONS

US is more accurate than clinical assessment of EFW in gravidas with obesity both for estimation of actual birthweight and prediction of abnormal birthweight. Universal late third-trimester or peripartum US for EFW should be considered in gravidas with obesity.

摘要

目的

胎儿估计体重(EFW)是分娩时的一个重要指标,因为出生体重异常的新生儿及其母亲发生分娩并发症的风险更高。关于肥胖孕妇中 EFW 最佳评估的数据不一致,且随着肥胖发生率的增加,明确这一问题至关重要。我们旨在比较肥胖孕妇中超声(US)衍生的 EFW 与临床 EFW 评估在预测新生儿出生体重方面的准确性。

方法

这项前瞻性队列研究纳入了因足月分娩而入院的肥胖孕妇及其单胎妊娠。EFW 是在入院时通过 US 生物测量或临床评估(Leopold 手法、Johnson 公式和 Insler 公式)确定的。我们的主要结局是准确的 EFW,定义为 EFW 与出生体重相差 500g 以内。次要结局包括预测小于胎龄儿(SGA)和大于胎龄儿(LGA)出生体重的能力。这些结局在所有 EFW 方法之间进行了比较。

结果

共纳入了 250 名体重指数中位数为 36.4kg/m 的肥胖孕妇。入院 US 在获得准确的 EFW 方面优于 Leopold 手法(81.6%对 74.5%,P=0.03)。当比较所有方法时,Johnson 公式和 Insler 公式的表现最差,分别只有 27.4%和 14.3%的病例能够准确预测 EFW。同样,US 衍生的 EFW 在预测 SGA 和 LGA 新生儿方面优于 Leopold 手法和宫底高度。

结论

在肥胖孕妇中,US 比临床 EFW 评估更准确,无论是在估计实际出生体重还是预测异常出生体重方面。肥胖孕妇应考虑在妊娠晚期或围产期进行通用的 US 测量 EFW。

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