Lepri Gemma, Markovic Milica, Bellando-Randone Silvia, Sebastiani Marco, Guiducci Serena
Division of Rheumatology, AOU Careggi, Department of Experimental and Clinical Medicine, University of Florence, Via delle Oblate 4, 50141 Florence, Italy.
Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Diagnostics (Basel). 2024 Jul 4;14(13):1430. doi: 10.3390/diagnostics14131430.
Lung involvement represents a fearful complication in rheumatoid arthritis (RA), potentially involving all compartments of the pulmonary system. Regarding interstitial lung disease (ILD), the HRCT represents the gold standard technique for its diagnosis; however, the examination is burdened by radiation exposure and high costs. In addition, although some risk factors for ILD are known, no algorithms exist to know which patients to submit to HRCT and when. In this context, lung ultrasound (LUS) showed promising results for at least 10 years, demonstrating correlation with high resolution computed tomography (HRCT) findings in other rheumatic diseases. Here, LUS may represent a screening test providing additional information to clinical examination and pulmonary function tests. The data deriving from LUS experience in other rheumatic diseases could steer the future towards the use of this technique also in RA patients, and in this review, we report the most relevant literature regarding LUS in RA-ILD.
肺部受累是类风湿关节炎（RA）中一种可怕的并发症，可能累及肺系统的所有部分。关于间质性肺疾病（ILD），高分辨率计算机断层扫描（HRCT）是其诊断的金标准技术；然而，该检查存在辐射暴露和成本高昂的问题。此外，尽管已知一些ILD的危险因素，但尚无算法来确定哪些患者应接受HRCT检查以及何时进行检查。在这种背景下，肺超声（LUS）至少在10年里显示出了有前景的结果，证明其与其他风湿性疾病的高分辨率计算机断层扫描（HRCT）结果具有相关性。在此，LUS可能代表一种筛查测试，可为临床检查和肺功能测试提供额外信息。来自其他风湿性疾病中LUS经验的数据可能会引领未来在RA患者中也使用这项技术，在本综述中，我们报告了关于RA-ILD中LUS的最相关文献。
