De Leval J, Chantraine A, Penders L
J Urol (Paris). 1985;91(1):1-12.
Treatment of non-neurologic dyssynergia is aimed at diminishing urethral sensory impulses or the motor component of the dysreflexia. Although formal proof of efficacy is lacking, urethral dilatation or meatoplasty in young girls is still used when an obstacle exists to passage of a balloon catheter. Functional obstruction is treated by Valium for its muscle-relaxant properties, alpha-blocking agents or biofeedback. In recent neurologic dyssynergia good results have been obtained after infiltrations of the para-urethral sphincter by an endo-urethral approach. Sphincterotomy is the treatment of choice when fibrosis has developed, particularly when the upper urinary tract is being affected: it can be performed earlier in cases where the dyssynergia fails to respond to well adapted conservative therapy. The site of section should be at 12 o'clock for anatomophysiologic reasons and to reduce the risk of impotence. The only treatment for rhabdosphincter deficiency is physiotherapy: reeducation and electric stimulation. Correctly instituted reeducation involves several phases: beginning with consciousness and learning of sphincter function it terminates in the automatic activation of the sphincter as for example during certain efforts. Results of several documented series in the urologic literature are encouraging.
非神经源性协同失调的治疗旨在减少尿道感觉冲动或反射亢进的运动成分。尽管缺乏疗效的确切证据,但当球囊导管通过存在障碍时,年轻女孩仍会采用尿道扩张术或尿道口成形术。功能性梗阻可使用具有肌肉松弛特性的安定、α受体阻滞剂或生物反馈疗法进行治疗。近年来,通过尿道内途径对尿道旁括约肌进行浸润注射后,神经源性协同失调取得了良好的效果。当出现纤维化,尤其是上尿路受到影响时,括约肌切开术是首选的治疗方法:在协同失调对适应性良好的保守治疗无反应的情况下,可更早进行手术。出于解剖生理学原因并降低阳痿风险,切开部位应在12点处。横纹括约肌缺陷的唯一治疗方法是物理治疗:再教育和电刺激。正确开展的再教育包括几个阶段:从意识到并学习括约肌功能开始,最终在某些努力过程中实现括约肌的自动激活。泌尿外科文献中多个有记录系列的结果令人鼓舞。