Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States.
Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States.
Addict Behav. 2024 Oct;157:108099. doi: 10.1016/j.addbeh.2024.108099. Epub 2024 Jul 3.
Electronic nicotine delivery systems (ENDS) are the most used tobacco product among adolescents and young adults (AYAs) and are increasingly used to vape cannabis. It is unclear what vaping devices and ENDS modifications are used most frequently by AYAs who vape both nicotine and cannabis.
AYAs (aged 14-29) reporting ENDS use in the past 30 days were recruited via Qualtrics (N = 1,011). We conducted three multivariable logistic regression models examining differences in likelihood of: 1) vaping cannabis in the past 30 days; 2) mixing cannabis and nicotine liquids; and 3) using nicotine devices to vape cannabis; based on type of vaping device used most often, controlling for age, socio-economic status, gender, race, frequency of ENDS use, and other cannabis use.
40 % (n = 405) of AYAs reported vaping both nicotine and cannabis in the past 30 days. AYAs who used vape pens most often were more likely to have vaped cannabis concentrates in the past 30 days compared to individuals using disposable vapes (aOR = 2.72, 95 %CI = 1.75-4.21, p < 0.001). AYAs who used open systems most often (i.e., vape pens, mods, or e-hookah) were more likely than individuals using closed systems (i.e., disposable vapes, rechargeable pods or cigalikes) to combine nicotine and cannabis e-liquids (aOR = 2.03, 95 %CI = 1.43-2.89, p < 0.001) or use a nicotine device to vape cannabis (aOR = 1.66, 95 %CI = 1.17-2.34, p = 0.005).
Co-use of cannabis and nicotine via similar devices, particularly vape pens and other open-systems, warrants collaborative regulatory efforts to mitigate co-use of both substances, with a particular need for increased regulation of cannabis vaping products.
电子尼古丁输送系统（ENDS）是青少年和年轻人（AYAs）中使用最多的烟草产品，并且越来越多地用于吸食大麻。目前尚不清楚同时吸食尼古丁和大麻的 AYAs 最常使用哪种蒸气设备和 ENDS 改装设备。
通过 Qualtrics 招募过去 30 天内报告使用 ENDS 的 AYAs（年龄 14-29 岁）（N=1011）。我们进行了三项多变量逻辑回归模型，以检查以下差异的可能性：1）过去 30 天内吸食大麻；2）混合大麻和尼古丁液体；3）使用尼古丁设备吸食大麻；根据最常使用的蒸气设备类型进行检查，并控制年龄、社会经济地位、性别、种族、ENDS 使用频率和其他大麻使用情况。
40%（n=405）的 AYAs 报告在过去 30 天内同时吸食尼古丁和大麻。与使用一次性蒸气器的人相比，最常使用蒸气笔的 AYAs 在过去 30 天内吸食大麻浓缩物的可能性更高（aOR=2.72，95%CI=1.75-4.21，p<0.001）。最常使用开放式系统（即蒸气笔、改装套件或电子烟）的 AYAs 比使用封闭式系统（即一次性蒸气器、可充电烟弹或雪茄型电子烟）更有可能将尼古丁和大麻电子液体混合在一起（aOR=2.03，95%CI=1.43-2.89，p<0.001），或者使用尼古丁设备吸食大麻（aOR=1.66，95%CI=1.17-2.34，p=0.005）。
通过类似设备同时使用大麻和尼古丁，特别是蒸气笔和其他开放式系统，需要协调监管努力来减轻这两种物质的共同使用，特别需要加强对大麻蒸气产品的监管。
