Seo J, Kurosawa T A, Borgeat K, Novo Matos J, Hutchinson J C, Arthurs O J, Luis Fuentes V
Animal Referral Centre (ARC Central), 8 Hereford Street, Freemans Bay, Auckland 1011, New Zealand; School of Veterinary Science, Massey University, Tennent Drive, Palmerston North 4410, New Zealand.
Dick White Referrals, Station Farm, London Road, Six Mile Bottom, Cambridgeshire CB8 0UH, United Kingdom.
J Vet Cardiol. 2024 Aug;54:30-37. doi: 10.1016/j.jvc.2024.05.003. Epub 2024 Jun 22.
Three cats were presented for unusual collapsing episodes. Echocardiography revealed a hypertrophic cardiomyopathy (HCM) phenotype in each cat. Continuous electrocardiographic monitoring showed that the clinical signs coincided with periods of severe ST-segment elevation in each cat. The first cat was treated with amlodipine and diltiazem but did not improve and was euthanized due to poor quality of life. Postmortem examination revealed cardiac lymphoma without obstructive coronary disease. The second cat was thought to have cardiac lymphoma, based on pericardial effusion cytology, and was euthanized before starting therapy. The third cat was diagnosed with HCM and left ventricular outflow tract obstruction and was treated with atenolol and diltiazem. This treatment reduced the frequency of episodic clinical signs, but the cat subsequently developed congestive heart failure and was euthanized. This case series describes clinical signs associated with severe ST elevation in cats with an HCM phenotype, and their outcomes. Continuous electrocardiographic monitoring was necessary to detect transient ST elevation in each case.
三只猫因出现异常的虚脱发作前来就诊。超声心动图显示每只猫均有肥厚型心肌病（HCM）表型。连续心电图监测表明，每只猫的临床症状均与严重ST段抬高期相符。第一只猫接受氨氯地平和地尔硫䓬治疗，但病情未改善，因生活质量差而实施安乐死。尸检显示为心脏淋巴瘤，无阻塞性冠状动脉疾病。根据心包积液细胞学检查，第二只猫被认为患有心脏淋巴瘤，在开始治疗前实施安乐死。第三只猫被诊断为肥厚型心肌病并伴有左心室流出道梗阻，接受阿替洛尔和地尔硫䓬治疗。该治疗降低了发作性临床症状的频率，但这只猫随后发展为充血性心力衰竭并被实施安乐死。本病例系列描述了具有肥厚型心肌病表型的猫出现严重ST段抬高相关的临床症状及其结局。在每个病例中，需要连续心电图监测来检测短暂的ST段抬高。
