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心脏手术后由根霉引起的胸骨骨髓炎和纵隔炎的成功治疗

Successful Treatment of Sternal Osteomyelitis and Mediastinitis Caused by Rhizopus Following Cardiac Surgery.

作者信息

Tiew Toot Chaw, Md Ali Nur Ayub, Ismail Muhammad Ishamuddin, Abdul Rahman Mohd Ramzisham, Ding Chuan Hun, Tzar Mohd Nizam

机构信息

Surgery, Faculty of Medicine, The National University of Malaysia, Kuala Lumpur, MYS.

Cardiothoracic Surgery, Faculty of Medicine, The National University of Malaysia, Kuala Lumpur, MYS.

出版信息

Cureus. 2024 Jun 13;16(6):e62312. doi: 10.7759/cureus.62312. eCollection 2024 Jun.

DOI:10.7759/cureus.62312
PMID:39006712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11246069/
Abstract

Sternal osteomyelitis and mediastinitis are rare yet severe complications post-cardiac surgery, often associated with significant morbidity and mortality. Fungal etiologies, particularly those caused by spp., are infrequent but can lead to aggressive infections. Here, we present the case of a 68-year-old male who developed sternal osteomyelitis and mediastinitis caused by spp. two weeks following coronary artery bypass grafting surgery. Debridement and pectoralis flap reconstruction were performed following clinical identification and confirmation with microbiological examinations and a CT scan. Prompt recognition, aggressive surgical intervention, and targeted antifungal therapy were crucial for successful management. This case underscores the importance of considering fungal pathogens, such as , in the differential diagnosis of post-cardiac surgery infections, as well as aggressive treatment to improve outcomes for affected patients.

摘要

胸骨骨髓炎和纵隔炎是心脏手术后罕见但严重的并发症,常伴有显著的发病率和死亡率。真菌病因,特别是由某些菌种引起的病因并不常见,但可导致侵袭性感染。在此,我们报告一例68岁男性患者,在冠状动脉搭桥手术后两周发生了由某些菌种引起的胸骨骨髓炎和纵隔炎。在临床诊断并经微生物检查和CT扫描确认后,进行了清创和胸大肌皮瓣重建术。及时识别、积极的手术干预和针对性抗真菌治疗对于成功治疗至关重要。该病例强调了在心脏手术后感染的鉴别诊断中考虑真菌病原体(如某些菌种)的重要性,以及积极治疗以改善受影响患者的预后。

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本文引用的文献

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