美国商业保险患者中嗜酸性食管炎的医疗资源利用和成本。
Healthcare Resource Utilization and Costs Associated With Eosinophilic Esophagitis Among Commercially Insured Patients in the United States.
机构信息
Worldwide Health Economics and Outcomes Research Unit, Bristol Myers Squibb, Princeton, New Jersey, USA.
Offshore Delivery, Mu Sigma, Bengaluru, India.
出版信息
Am J Gastroenterol. 2024 Nov 1;119(11):2326-2330. doi: 10.14309/ajg.0000000000002901. Epub 2024 Jun 24.
INTRODUCTION
To evaluate real-world healthcare resource utilization (HCRU) and costs associated with eosinophilic esophagitis (EoE) in the United States.
METHODS
Retrospective case-control cohort analysis of Optum Clinformatics claims data (January 2008-September 2020) comparing unadjusted and adjusted HCRU (visits per 1,000 patients per month) and all-cause costs (per patient per month).
RESULTS
Patients with EoE incurred significantly higher monthly HCRU (adjusted Δ [95% confidence interval]: inpatient visits, 2.8 [0.1-4.0]; emergency department visits, 14.7 [4.3-32.1]; outpatient visits, 388.8 [362.1-418.0]); and costs ($581 [$421-$600]) vs matched controls (all P < 0.001).
DISCUSSION
EoE imposes substantial economic burden. More effective and targeted treatments that improve outcomes for patients are needed.
简介
评估美国嗜酸性食管炎（EoE）的实际医疗资源利用（HCRU）和成本。
方法
利用 Optum Clinformatics 索赔数据（2008 年 1 月至 2020 年 9 月）进行回顾性病例对照队列分析，比较未经调整和调整后的 HCRU（每月每千名患者就诊次数）和全因成本（每名患者每月）。
结果
EoE 患者的每月 HCRU 明显更高（调整后Δ[95%置信区间]：住院就诊次数 2.8[0.1-4.0]；急诊就诊次数 14.7[4.3-32.1]；门诊就诊次数 388.8[362.1-418.0]）和成本（581 美元[421-600 美元]）与匹配对照组相比差异均有统计学意义（均 P<0.001）。
讨论
EoE 造成了巨大的经济负担。需要更有效和有针对性的治疗方法，以改善患者的预后。
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